Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20281069 | 0.95 | ALDH1A1 (0.46) | ALDH1A1KDM4EPOLBUSP2ALOX15 | |
| SCHEMBL21618568 | 0.91 | ALDH1A1 (0.43) | ALDH1A1KDM4EPOLBUSP2ALOX15 | |
| SCHEMBL20280876 | 0.91 | ALDH1A1 (0.43) | ALDH1A1KDM4EPOLBUSP2ALOX15 | |
| SCHEMBL20281066 | 0.90 | ALDH1A1 (0.42) | ALDH1A1KDM4EPOLBUSP2ALOX15 | |
| SCHEMBL20280652 | 0.89 | ALDH1A1 (0.39) | ALDH1A1KDM4EPOLBUSP2ALOX15 | |
| SCHEMBL21618567 | 0.85 | ALDH1A1 (0.35) | ALDH1A1KDM4EPOLBUSP2ALOX15 | |
| SCHEMBL21618562 | 0.83 | ALDH1A1 (0.44) | ALDH1A1KDM4EPOLBUSP2ALOX15 | |
| SCHEMBL20280886 | 0.82 | TSHR (0.47) | ALDH1A1KDM4EPOLBUSP2ALOX15 | |
| SCHEMBL20281075 | 0.82 | ALDH1A1 (0.43) | ALDH1A1KDM4EPOLBUSP2ALOX15 | |
| SCHEMBL20280975 | 0.80 | ALDH1A1 (0.36) | ALDH1A1KDM4EPOLBUSP2ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10793533-B2 | Dimeric contrast agents | BRACCO IMAGING S.P.A. (IT) | 2020-10-06 | — | — | US | disclosed |
| US-20200017453-A1 | DIMERIC CONTRAST AGENTS | BRACCO IMAGING S.P.A. (IT) | 2020-01-16 | — | — | US | disclosed |
| WO-2018108780-A1 | DIMERIC CONTRAST AGENTS | BRACCO IMAGING SPA (IT) | 2018-06-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10793533-B2 | Dimeric contrast agents | CALCOCO2, SLC39A14, NOD2 | ALDH1A1 4705/4885KDM4E 4112/4885POLB 3512/4885 |
| US-20200017453-A1 | DIMERIC CONTRAST AGENTS | CALCOCO2, SLC39A14, NOD2 | ALDH1A1 4705/4885KDM4E 4112/4885POLB 3512/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.