Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC28A1 | O00337 | 1/20 | 0.43 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.43 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.43 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.43 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.41 |
| ▸ | DUT | P33316 | 4/20 | 0.40 |
| ▸ | P2RY2 | P41231 | 8/20 | 0.38 |
| ▸ | P2RY6 | Q15077 | 4/20 | 0.36 |
| ▸ | P2RY4 | P51582 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13531639 | 1.00 | SLC28A1 (0.43) | SLC28A1SLC28A2SLC29A1SLC28A3CRBN | |
| SCHEMBL9853759 | 1.00 | SLC28A1 (0.43) | SLC28A1SLC28A2SLC29A1SLC28A3CRBN | |
| SCHEMBL8038615 | 0.81 | TK1 (0.46) | — | |
| SCHEMBL12154833 | 0.81 | DUT (0.41) | SLC28A1SLC28A2SLC29A1SLC28A3CRBN | |
| SCHEMBL13939558 | 0.81 | SLC28A1 (0.43) | SLC28A1SLC28A2SLC29A1SLC28A3CRBN | |
| SCHEMBL14102265 | 0.81 | SLC28A1 (0.40) | SLC28A1SLC28A2SLC29A1SLC28A3CRBN | |
| SCHEMBL9452795 | 0.81 | SLC28A1 (0.46) | SLC28A1SLC28A2SLC29A1SLC28A3DUT | |
| SCHEMBL16855538 | 0.81 | DUT (0.41) | SLC28A1SLC28A2SLC29A1SLC28A3CRBN | |
| SCHEMBL31589522 | 0.79 | SLC28A1 (0.44) | SLC28A1SLC28A2SLC29A1SLC28A3DUT | |
| SCHEMBL30618187 | 0.79 | SLC28A1 (0.44) | SLC28A1SLC28A2SLC29A1SLC28A3DUT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018107236-A1 | NOVEL COMPOUNDS AS ANTI-MYCOBACTERIALS | THE UNIVERSITY OF SYDNEY (AU) | 2018-06-21 | — | — | WO | disclosed |