Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.49 |
| ▸ | PTPN6 | P29350 | 3/20 | 0.49 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.49 |
| ▸ | ACP1 | P24666 | 8/20 | 0.47 |
| ▸ | PTPN12 | Q05209 | 4/20 | 0.47 |
| ▸ | PTPN13 | Q12923 | 3/20 | 0.47 |
| ▸ | SSU72 | Q9NP77 | 3/20 | 0.47 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | TACR1 | P25103 | 1/20 | 0.43 |
| ▸ | TACR3 | P29371 | 1/20 | 0.43 |
| ▸ | NAAA | Q02083 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20281608 | 0.91 | SRC (0.51) | SRCPTPN1PTPN6PTPN11ACP1 | |
| SCHEMBL11630026 | 0.81 | SRC (0.58) | SRCPTPN1PTPN6PTPN11ACP1 | |
| SCHEMBL20281612 | 0.78 | SRC (0.63) | SRCPTPN1PTPN6PTPN11ACP1 | |
| SCHEMBL17596567 | 0.76 | CES2 (0.50) | CNR1CNR2TACR1TACR3NAAA | |
| SCHEMBL20281457 | 0.74 | CA12 (0.46) | SRCACP1PTPN12PTPN13SSU72 | |
| Hydrochloric Acid SCHEMBL11651001 | 0.74 | CNR1 (0.46) | CNR1CNR2TACR1TACR3NAAA | |
| SCHEMBL9706850 | 0.72 | SRC (0.70) | SRCPTPN1PTPN6PTPN11ACP1 | |
| SCHEMBL13619014 | 0.72 | SRC (0.70) | SRCPTPN1PTPN6PTPN11ACP1 | |
| SCHEMBL20869602 | 0.72 | SRC (1.00) | SRCPTPN1PTPN6PTPN11ACP1 | |
| SCHEMBL11166146 | 0.72 | SRC (1.00) | SRCPTPN1PTPN6PTPN11ACP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180170861-A1 | SMALL MOLECULE INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES AND USED THEREOF | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION | 2018-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180170861-A1 | SMALL MOLECULE INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES AND USED THEREOF | PTPA, EPM2A, PTPRA | SRC 201/4885PTPN1 33/4885PTPN6 28/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.