Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MBNL1 | Q9NR56 | 1/20 | 0.39 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22806612 | 0.80 | ALDH1A1 (0.46) | ALDH1A1HPGDHTTKDM4EGAA | |
| SCHEMBL11731221 | 0.79 | ALDH1A1 (0.49) | ALDH1A1HPGDHTTKDM4EGAA | |
| SCHEMBL14352717 | 0.78 | KMT2A (0.50) | ALDH1A1HPGDHTTKDM4EGAA | |
| SCHEMBL28214650 | 0.77 | ALDH1A1 (0.46) | ALDH1A1HPGDHTTKDM4EGAA | |
| SCHEMBL14360658 | 0.76 | ALDH1A1 (0.45) | ALDH1A1HPGDKDM4EGAAGLA | |
| SCHEMBL28118305 | 0.76 | GAA (0.56) | ALDH1A1HPGDHTTKDM4EGAA | |
| SCHEMBL30162825 | 0.74 | HTT (0.44) | ALDH1A1HPGDHTTKDM4EGAA | |
| SCHEMBL2172354 | 0.74 | ALDH1A1 (0.56) | ALDH1A1HPGDKDM4EGAAGLA | |
| SCHEMBL29204419 | 0.73 | ALDH1A1 (0.43) | ALDH1A1HPGDHTTKDM4EGAA | |
| Hydrochloric Acid SCHEMBL28823670 | 0.73 | ALDH1A1 (0.41) | ALDH1A1HPGDHTTKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130116206-A1 | QUINOLINE DERIVATIVES USED AS PET IMAGING AGENTS | IMPERIAL INNOVATIONS LIMITED (GB) | 2013-05-09 | — | — | US | disclosed |
| EP-2516403-A1 | QUINOLINE DERIVATIVES USED AS PET IMAGING AGENTS | Imperial Innovations Limited (GB) | 2012-10-31 | — | — | EP | disclosed |
| WO-2011077095-A1 | QUINOLINE DERIVATIVES USED AS PET IMAGING AGENTS | IMPERIAL INNOVATIONS LIMITED (GB) | 2011-06-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130116206-A1 | QUINOLINE DERIVATIVES USED AS PET IMAGING AGENTS | ERBB2, EGFR, ERBB4 | ALDH1A1 3113/4885HPGD 1470/4885HTT 1641/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.