Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 8/20 | 0.46 |
| ▸ | RARB | P10826 | 9/20 | 0.43 |
| ▸ | THRA | P10827 | 7/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | RARA | P10276 | 2/20 | 0.38 |
| ▸ | RARG | P13631 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20286019 | 0.99 | THRB (0.46) | THRBRARBTHRAMEN1KMT2A | |
| SCHEMBL20285996 | 0.96 | THRB (0.42) | THRBRARBTHRAMEN1KMT2A | |
| SCHEMBL20286015 | 0.92 | THRB (0.43) | THRBRARBALDH1A1HPGDTSHR | |
| SCHEMBL20286016 | 0.91 | THRB (0.36) | THRBRARBALDH1A1MAPTHPGD | |
| SCHEMBL20286004 | 0.90 | FFAR4 (0.38) | THRBRARBALDH1A1HPGDTSHR | |
| SCHEMBL19796833 | 0.87 | THRB (0.48) | THRBRARBTHRAMEN1KMT2A | |
| SCHEMBL19796837 | 0.85 | RARB (0.48) | THRBRARBTHRAMEN1KMT2A | |
| SCHEMBL19796934 | 0.84 | THRB (0.45) | THRBRARBTHRAMEN1KMT2A | |
| SCHEMBL19796719 | 0.83 | THRB (0.46) | THRBRARBTHRAMEN1KMT2A | |
| SCHEMBL19796726 | 0.83 | THRB (0.46) | THRBRARBTHRAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180171231-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2018-06-21 | — | — | US | disclosed |