Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 5/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | RARB | P10826 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 2/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | VDR | P11473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20286016 | 0.95 | THRB (0.36) | THRBALOX5GABRA1GABRB2TSHR | |
| SCHEMBL20285996 | 0.94 | THRB (0.42) | THRBTSHRHPGDRARBCNR2 | |
| SCHEMBL20286004 | 0.94 | FFAR4 (0.38) | THRBALOX5GABRA1GABRB2TSHR | |
| SCHEMBL20286019 | 0.93 | THRB (0.46) | THRBTSHRHPGDRARBMCL1 | |
| SCHEMBL20286014 | 0.92 | THRB (0.46) | THRBTSHRHPGDALDH1A1RARB | |
| SCHEMBL19796293 | 0.84 | CNR2 (0.41) | THRBALOX5GABRA1GABRB2TSHR | |
| SCHEMBL19796379 | 0.84 | THRB (0.48) | THRBALOX5GABRA1GABRB2TSHR | |
| SCHEMBL19796441 | 0.84 | THRB (0.48) | THRBALOX5GABRA1GABRB2TSHR | |
| SCHEMBL19796436 | 0.83 | THRB (0.47) | THRBALOX5GABRA1GABRB2TSHR | |
| SCHEMBL19796375 | 0.82 | THRB (0.49) | THRBALOX5TSHRHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180171231-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2018-06-21 | — | — | US | disclosed |