SCHEMBL20286642

SCHEMBL20286642

CCc1ccc(-c2ccc(-c3cc(C)c(F)c(C)c3)c(C)c2)c(C)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.36
ALDH1A1 P00352 1/20 0.36
LMNA P02545 1/20 0.36
MAPT P10636 1/20 0.36
MAPK1 P28482 1/20 0.36
RAB9A P51151 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
ESR1 P03372 1/20 0.35
ESR2 Q92731 1/20 0.35
RARB P10826 1/20 0.35
PDE3B Q13370 3/20 0.35
PDE3A Q14432 3/20 0.35
MMP2 P08253 1/20 0.34
MMP3 P08254 1/20 0.34
AKR1C3 P42330 1/20 0.33
AKR1C2 P52895 1/20 0.33
PDE2A O00408 1/20 0.33
TRPA1 O75762 1/20 0.33
PPARA Q07869 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12603798 0.82 PTGS1 (0.44) NPC1ALDH1A1LMNAMAPTMAPK1
SCHEMBL20286644 0.79 FFAR4 (0.38) MMP2MMP3PDE2APPARAPDK2
SCHEMBL20286643 0.78 ESR2 (0.43) NPC1MAPTRAB9AESR1ESR2
SCHEMBL14371121 0.77 PTGS2 (0.41) S1PR1S1PR3PTGS1PTGS2
SCHEMBL21558709 0.77 S1PR1 (0.43) ESR1ESR2RARBMMP2MMP3
SCHEMBL12603788 0.75 SLC1A3 (0.41) NPC1ALDH1A1LMNAMAPTMAPK1
SCHEMBL12603787 0.75 PPARA (0.50) ALDH1A1MAPTAKR1C3AKR1C2PPARA
SCHEMBL17295140 0.74 PTGS2 (0.41) LMNAESR1ESR2PDE2ATRPA1
SCHEMBL12603795 0.74 PTGS1 (0.43) NPC1ALDH1A1LMNAMAPTMAPK1
SCHEMBL10520096 0.74 ESR2 (0.55) NPC1ALDH1A1LMNAMAPTMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180171234-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE USING THE SAME DIC CORPORATION (JP) 2018-06-21 US disclosed