Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 3/20 | 0.43 |
| ▸ | ESR1 | P03372 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 4/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 4/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CTSA | P10619 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17471813 | 0.89 | MAPT (0.36) | ESR2ESR1GAAMAPTPDE3B | |
| SCHEMBL91804 | 0.85 | AKR1C3 (0.41) | ESR2ESR1GAAMAPTPDE3B | |
| SCHEMBL91795 | 0.82 | AKR1C3 (0.45) | ESR2ESR1GAAMAPTPDE3B | |
| SCHEMBL20286640 | 0.81 | ESR1 (0.36) | ESR2ESR1PDE3BPDE3A | |
| SCHEMBL26529413 | 0.81 | ESR2 (0.47) | ESR2ESR1GAAMAPTTP53 | |
| SCHEMBL18553115 | 0.80 | AKR1C3 (0.46) | ESR2ESR1GAAMAPTPDE3B | |
| SCHEMBL20976650 | 0.79 | RPS6KA3 (0.39) | PDE3BPDE3AAKR1C3AKR1C2PTGS2 | |
| SCHEMBL21021329 | 0.79 | ESRRA (0.38) | GAAMAPTTP53TDP1MEN1 | |
| SCHEMBL13906327 | 0.79 | ACHE (0.50) | ESR2ESR1GAAMAPTPDE3B | |
| SCHEMBL11223633 | 0.78 | ESR1 (0.42) | ESR2ESR1GAAMAPTPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180171234-A1 | LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE USING THE SAME | DIC CORPORATION (JP) | 2018-06-21 | — | — | US | disclosed |