SCHEMBL11223633

SCHEMBL11223633

Cc1ccc(-c2ccc(Oc3ccc(-c4ccc(C)cc4C)cc3C)c(C)c2)c(C)c1

nearest known ligand 0.42

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.42
ESR2 Q92731 1/20 0.42
HTR1A P08908 2/20 0.41
HTR3A P46098 2/20 0.41
GAA P10253 2/20 0.38
ACHE P22303 1/20 0.38
CTSA P10619 1/20 0.38
MAPT P10636 2/20 0.37
L3MBTL1 Q9Y468 2/20 0.36
HPGD P15428 1/20 0.36
TSHR P16473 1/20 0.36
MAPK1 P28482 1/20 0.36
MET P08581 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2C19 P33261 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
PTGS2 P35354 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31666386 0.83 HTR1A (0.50) HTR1AHTR3AGAAACHEMAPT
SCHEMBL4950654 0.83 HTR1A (0.50) HTR1AHTR3AGAAACHEMAPT
SCHEMBL26529413 0.79 ESR2 (0.47) ESR1ESR2GAAMAPTPTGS2
SCHEMBL20286643 0.78 ESR2 (0.43) ESR1ESR2GAACTSAMAPT
SCHEMBL284409 0.77 ESR2 (0.47) ESR1ESR2GAAACHEMAPT
SCHEMBL18722306 0.74 ESR2 (0.45) ESR1ESR2GAAACHEMAPT
Phosphoric Acid SCHEMBL3268955 0.74 HPGD (0.40) HTR1AHTR3AGAAMAPTL3MBTL1
SCHEMBL10339273 0.74 HTR1A (0.37) HTR1AHTR3AGAAACHEMAPT
SCHEMBL8737305 0.74 HTR1A (0.55) HTR1AHTR3AGAAMAPTL3MBTL1
SCHEMBL5334234 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4341526-A Levelling agent and process of levelling for the disperse dyeing of hydrophobic materials MOBAY CHEMICAL CORPORATION (US) 1982-07-27 US disclosed