SCHEMBL2028748

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2037866	0.87	ALDH1A1 (0.46)	PPARGALDH1A1GAACCR2LMNA
	SCHEMBL2032678	0.83	SMN1; SMN2 (0.47)	PPARGALDH1A1GAACCR2LMNA
	SCHEMBL2034985	0.82	PPARG (0.56)	PPARGALDH1A1GAACCR2PIK3CB
	SCHEMBL2031882	0.78	PPARG (0.52)	PPARGALDH1A1GAACCR2LMNA
	SCHEMBL2031472	0.76	PPARG (0.59)	PPARGLMNAMEN1KMT2AMAPT
	SCHEMBL2036828	0.75	PPARG (0.45)	PPARGALDH1A1GAACCR2LMNA
	SCHEMBL2568163	0.73	GAA (0.64)	ALDH1A1GAACCR2LMNAMAPK1
	SCHEMBL2034935	0.72	PPARG (0.56)	PPARGGAALMNA
	SCHEMBL12585171	0.72	ALDH1A1 (0.46)	ALDH1A1LMNASMN1; SMN2MEN1KMT2A
	SCHEMBL2035210	0.70	ACLY (0.50)	—

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.