Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | CTSD | P07339 | 1/20 | 0.30 |
| ▸ | CTSL | P07711 | 1/20 | 0.30 |
| ▸ | CTSB | P07858 | 1/20 | 0.30 |
| ▸ | CTSS | P25774 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1771686 | 0.79 | HDAC6 (0.38) | HDAC6HDAC1HDAC2DGAT1NFKB1 | |
| SCHEMBL1706932 | 0.79 | HDAC6 (0.38) | HDAC6HDAC1HDAC2DGAT1NFKB1 | |
| SCHEMBL8356008 | 0.78 | HDAC6 (0.36) | HDAC6HDAC1HDAC2DGAT1NFKB1 | |
| SCHEMBL12258769 | 0.78 | HDAC6 (0.36) | HDAC6HDAC1HDAC2DGAT1NFKB1 | |
| SCHEMBL1793739 | 0.77 | ATM (0.30) | — | |
| SCHEMBL432112 | 0.77 | HDAC6 (0.37) | HDAC6HDAC1HDAC2DGAT1NFKB1 | |
| SCHEMBL28097176 | 0.77 | HDAC6 (0.37) | HDAC6HDAC1HDAC2DGAT1NFKB1 | |
| SCHEMBL15719423 | 0.77 | ALDH1A1 (0.32) | DGAT1 | |
| SCHEMBL10023648 | 0.75 | HDAC6 (0.36) | HDAC6HDAC1HDAC2DGAT1CA14 | |
| Hydrochloric Acid SCHEMBL5679482 | 0.75 | HDAC6 (0.36) | HDAC6HDAC1HDAC2DGAT1CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3147283-B1 | HYDRAZINE COMPOUND AS BLOOD COAGULATION FACTOR XA INHIBITOR | NORTH CHINA PHARMACEUTICAL COMPANY LTD (CN) | 2022-08-17 | — | — | EP | disclosed |
| CN-109776464-A | The preparation method of furan tebufenozide, intermediate and preparation method thereof | 江苏省农药研究所股份有限公司 | 2019-05-21 | — | — | CN | disclosed |
| EP-3147283-A1 | HYDRAZINE COMPOUND AS BLOOD COAGULATION FACTOR Xa INHIBITOR | North China Pharmaceutical Company., Ltd. (CN) | 2017-03-29 | — | — | EP | disclosed |
| EP-2516434-A1 | FUSED HETEROAROMATIC PYRROLIDINONES AS SYK INHIBITORS | Takeda Pharmaceutical Company Limited (JP) | 2012-10-31 | — | — | EP | disclosed |
| WO-2011079051-A1 | FUSED HETEROAROMATIC PYRROLIDINONES AS SYK INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-06-30 | — | — | WO | disclosed |