Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.30 |
| ▸ | RELA | Q04206 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1706932 | 0.81 | HDAC6 (0.38) | HDAC6HDAC1HDAC2DGAT1CA14 | |
| SCHEMBL1771686 | 0.81 | HDAC6 (0.38) | HDAC6HDAC1HDAC2DGAT1CA14 | |
| SCHEMBL432112 | 0.79 | HDAC6 (0.37) | HDAC6HDAC1HDAC2DGAT1CA14 | |
| SCHEMBL3716921 | 0.78 | HDAC6 (0.39) | HDAC6HDAC1HDAC2DGAT1CA14 | |
| SCHEMBL2028779 | 0.77 | HDAC6 (0.36) | HDAC6HDAC1HDAC2DGAT1CA14 | |
| SCHEMBL17844334 | 0.77 | HDAC6 (0.36) | HDAC6HDAC1HDAC2DGAT1CA14 | |
| SCHEMBL16375890 | 0.77 | HDAC6 (0.36) | HDAC6HDAC1HDAC2DGAT1CA14 | |
| Hydrochloric Acid SCHEMBL5679482 | 0.77 | HDAC6 (0.36) | HDAC6HDAC1HDAC2DGAT1CA14 | |
| SCHEMBL10023648 | 0.77 | HDAC6 (0.36) | HDAC6HDAC1HDAC2DGAT1CA14 | |
| SCHEMBL28394 | 0.76 | HDAC6 (0.38) | HDAC6HDAC1HDAC2DGAT1CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105919987-A | N-acyloxysulfonamide And N-hydroxy-n-acylsulfonamide Derivatives And Use Thereof | 约翰斯霍普金斯大学 | 2016-09-07 | — | — | CN | disclosed |