SCHEMBL2028817

SCHEMBL2028817

C=C(C)C(=O)OCCCCCCCCCCCOc1ccc(C=C(C#N)c2cc(OC)c(OC)c(OC)c2)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TUBB1 Q9H4B7 6/20 0.60
TUBB4A P04350 5/20 0.60
TUBB P07437 5/20 0.60
TUBA3C P0DPH7 5/20 0.60
TUBA1B P68363 5/20 0.60
TUBA4A P68366 5/20 0.60
TUBB4B P68371 5/20 0.60
TUBB3 Q13509 5/20 0.60
TUBB2A Q13885 5/20 0.60
TUBB8 Q3ZCM7 5/20 0.60
TUBA3E Q6PEY2 5/20 0.60
TUBA1A Q71U36 5/20 0.60
TUBA1C Q9BQE3 5/20 0.60
TUBB6 Q9BUF5 5/20 0.60
TUBB2B Q9BVA1 5/20 0.60
POLB P06746 1/20 0.50
APEX1 P27695 1/20 0.50
HTT P42858 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
NQO1 P15559 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2028815 1.00 TUBB1 (0.60) TUBB1TUBB4ATUBBTUBA3CTUBA1B
SCHEMBL4652668 0.91 HTT (0.53) TUBB1TUBB4ATUBBTUBA3CTUBA1B
SCHEMBL4652665 0.91 HTT (0.53) TUBB1TUBB4ATUBBTUBA3CTUBA1B
SCHEMBL14723015 0.90 POLB (0.54) TUBB1TUBB4ATUBBTUBA3CTUBA1B
SCHEMBL14723014 0.90 POLB (0.54) TUBB1TUBB4ATUBBTUBA3CTUBA1B
SCHEMBL4651506 0.90 TUBB4A (0.54) TUBB1TUBB4ATUBBTUBA3CTUBA1B
SCHEMBL4651503 0.90 TUBB4A (0.54) TUBB1TUBB4ATUBBTUBA3CTUBA1B
SCHEMBL15862412 0.90 TUBB4A (0.54) TUBB1TUBB4ATUBBTUBA3CTUBA1B
SCHEMBL14734631 0.90 TUBB4A (0.54) TUBB1TUBB4ATUBBTUBA3CTUBA1B
SCHEMBL4651509 0.87 POLB (0.58) TUBB1TUBB4ATUBBTUBA3CTUBA1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7959990-B2 Adjustment of liquid crystals; oligomers, dendrimers, or polymer in solution is applied to support; crosslinking by radiation or polarized light ROLIC AG (CH) 2011-06-14 US disclosed
EP-1928979-B1 FUNCTIONALIZED PHOTOREACTIVE COMPOUNDS ROLIC AG (CH) 2009-03-04 EP disclosed
US-20080274304-A1 Functionalized Photoreactive Compounds ROLIC AG (CH) 2008-11-06 US disclosed
EP-1975687-A1 Method of uniform and defect free liquid crystal aligning layers Rolic AG (CH) 2008-10-01 EP disclosed
EP-1928979-A1 FUNCTIONALIZED PHOTOREACTIVE COMPOUNDS Rolic AG (CH) 2008-06-11 EP disclosed
WO-2007033506-A1 FUNCTIONALIZED PHOTOREACTIVE COMPOUNDS ROLIC AG (CH) 2007-03-29 WO disclosed
EP-1764405-A1 Functionalized photoreactive compounds Rolic AG (CH) 2007-03-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080274304-A1 Functionalized Photoreactive Compounds PCNA, PIN1, MAP1LC3C TUBB1 335/4885TUBB4A 124/4885TUBB 370/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.