Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26288724 | 0.86 | — | — | |
| SCHEMBL29291655 | 0.82 | NPC1 (0.45) | NPC1 | |
| SCHEMBL653814 | 0.82 | ODC1 (0.41) | NPC1 | |
| SCHEMBL24899987 | 0.80 | CPB2 (0.32) | NPC1 | |
| SCHEMBL6318844 | 0.80 | NPC1 (0.48) | NPC1 | |
| SCHEMBL15108551 | 0.80 | NPC1 (0.48) | NPC1 | |
| SCHEMBL15856478 | 0.78 | NPC1 (0.40) | NPC1 | |
| SCHEMBL8060908 | 0.74 | NPC1 (0.47) | NPC1 | |
| SCHEMBL13401898 | 0.74 | SMN1; SMN2 (0.38) | — | |
| SCHEMBL19576089 | 0.74 | SMN1; SMN2 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018112122-A1 | METHODS OF IDENTIFYING AND TREATING TUMORS WITH SIGMA1 INHIBITORS | DREXEL UNIVERSITY (US) | 2018-06-21 | — | — | WO | disclosed |