Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20286038 | 0.67 | — | — | |
| SCHEMBL8394026 | 0.64 | MITF (0.34) | — | |
| SCHEMBL14345128 | 0.63 | PTPN1 (0.36) | PTPN1 | |
| SCHEMBL20288249 | 0.59 | MEN1 (0.38) | PTPN1 | |
| SCHEMBL7639176 | 0.57 | ABCB1 (0.31) | — | |
| SCHEMBL304424 | 0.56 | CDC25A (0.32) | — | |
| SCHEMBL14522435 | 0.54 | TSHR (0.30) | — | |
| SCHEMBL4202273 | 0.54 | — | — | |
| SCHEMBL25442498 | 0.54 | MAP4K1 (0.38) | — | |
| SCHEMBL25442500 | 0.54 | MAP4K1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180170891-A1 | 4H-Pyran Compounds as Insulin-Regulated Aminopeptidase (IRAP) Inhibitors | MONASH UNIVERSITY (AU) | 2018-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180170891-A1 | 4H-Pyran Compounds as Insulin-Regulated Aminopeptidase (IRAP) Inhibitors | IAPP, ENPEP, DNPEP | PTPN1 1595/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.