Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adenosine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 known ✓ | P0DMS8 | 4/20 | 1.00 |
| ▸ | ADORA2A known ✓ | P29274 | 1/20 | 1.00 |
| ▸ | ADORA2B known ✓ | P29275 | 1/20 | 1.00 |
| ▸ | ADORA1 known ✓ | P30542 | 1/20 | 1.00 |
| ▸ | DPP4 | P27487 | 1/20 | 1.00 |
| ▸ | MEN1 | O00255 | 1/20 | 1.00 |
| ▸ | SLC28A1 | O00337 | 1/20 | 1.00 |
| ▸ | MAP3K7 | O43318 | 1/20 | 1.00 |
| ▸ | SLC28A2 | O43868 | 1/20 | 1.00 |
| ▸ | GAPDH | P04406 | 1/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 1/20 | 1.00 |
| ▸ | STAT6 | P42226 | 1/20 | 1.00 |
| ▸ | PI4KA | P42356 | 1/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 1/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 1.00 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 1.00 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 1.00 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 1.00 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 1.00 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adenosine SCHEMBL14496806 | 1.00 | ADORA3 (1.00) | ADORA3DPP4MEN1SLC28A1MAP3K7 | |
| Adenosine SCHEMBL10361572 | 1.00 | ADORA3 (1.00) | ADORA3DPP4MEN1SLC28A1MAP3K7 | |
| Vidarabine SCHEMBL110914 | 1.00 | ADORA3 (1.00) | ADORA3DPP4MEN1SLC28A1MAP3K7 | |
| Adenosine SCHEMBL20399009 | 1.00 | ADORA3 (1.00) | ADORA3DPP4MEN1SLC28A1MAP3K7 | |
| Adenosine SCHEMBL24538665 | 1.00 | ADORA3 (1.00) | ADORA3DPP4MEN1SLC28A1MAP3K7 | |
| Adenosine SCHEMBL23804425 | 1.00 | ADORA3 (1.00) | ADORA3DPP4MEN1SLC28A1MAP3K7 | |
| Adenosine SCHEMBL2403831 | 1.00 | ADORA3 (1.00) | ADORA3DPP4MEN1SLC28A1MAP3K7 | |
| Adenosine SCHEMBL23420216 | 1.00 | ADORA3 (1.00) | ADORA3DPP4MEN1SLC28A1MAP3K7 | |
| Adenosine SCHEMBL4403412 | 1.00 | ADORA3 (1.00) | ADORA3DPP4MEN1SLC28A1MAP3K7 | |
| Adenosine SCHEMBL329845 | 1.00 | ADORA3 (1.00) | ADORA3DPP4MEN1SLC28A1MAP3K7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4612294-A2 | MODIFIED SHORT INTERFERING NUCLEIC ACID (SINA) MOLECULES AND USES THEREOF | Aligos Therapeutics, Inc. (US) | 2025-09-10 | — | — | EP | disclosed |
| US-10781472-B2 | Systems and methods for determining cyclic nucleotide concentration and related pathway activation | PROMEGA CORPORATION (US) | 2020-09-22 | — | — | US | disclosed |
| US-20190024114-A1 | METHOD OF PRODUCING A PRODUCTION CELL LINE | BAUER, ANTON (AT) | 2019-01-24 | — | — | US | disclosed |
| US-20180340210-A1 | METHODS FOR CYCLIC NUCLEOTIDE DETERMINATION | JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT | 2018-11-29 | — | — | US | disclosed |
| EP-3402886-A1 | METHOD OF PRODUCING A PRODUCTION CELL LINE | Bauer, Anton (AT) | 2018-11-21 | — | — | EP | disclosed |
| US-10000792-B2 | Methods for cyclic nucleotide determination | PROMEGA CORPORATION (US) | 2018-06-19 | — | — | US | disclosed |
| WO-2017121896-A1 | METHOD OF PRODUCING A PRODUCTION CELL LINE | BAUER ANTON (AT) | 2017-07-20 | — | — | WO | disclosed |
| US-8728800-B2 | Assay method | AXIS SHIELD ASA (NO) | 2014-05-20 | — | — | US | disclosed |
| WO-2012166743-A2 | FUSION PROTEINS OF CILIATE GRANULE LATTICE PROTEINS, GRANULAR PROTEIN PARTICLES THEREOF, AND USES THEREFOR | TETRAGENETICS, INC. (US) | 2012-12-06 | — | — | WO | disclosed |
| EP-2400029-A2 | Methods for cyclic nucleotide determination | Promega Corporation (US) | 2011-12-28 | — | — | EP | disclosed |
| EP-1963366-B1 | METHODS FOR CYCLIC NUCLEOTIDE DETERMINATION | PROMEGA CORP (US) | 2011-09-14 | — | — | EP | disclosed |
| US-20110129821-A1 | METHODS FOR CYCLIC NUCLEOTIDE DETERMINATION | PROMEGA CORPORATION (US) | 2011-06-02 | — | — | US | disclosed |
| US-20070172896-A1 | Methods for cyclic nucleotide determination | PROMEGA CORPORATION (US) | 2007-07-26 | — | — | US | disclosed |
| EP-0247145-B1 | MULTIPLY-AMPLIFIABLE VECTORS FOR HIGH LEVEL EXPRESSION OF EXOGENOUS DNA | GENETICS INSTITUTE, INC. (US) | 1992-02-26 | — | — | EP | disclosed |
| EP-0221955-A4 | HIGH LEVEL AMPLIFICATION AND EXPRESSION OF EXOGENOUS DNA. | GENETICS INST (US) | 1988-12-22 | — | — | EP | disclosed |
| EP-0247145-A4 | MULTIPLY-AMPLIFIABLE VECTORS FOR HIGH LEVEL EXPRESSION OF EXOGENOUS DNA. | GENETICS INST (US) | 1988-11-23 | — | — | EP | disclosed |
| EP-0247145-A1 | MULTIPLY-AMPLIFIABLE VECTORS FOR HIGH LEVEL EXPRESSION OF EXOGENOUS DNA. | GENETICS INST (US) | 1987-12-02 | — | — | EP | disclosed |
| EP-0221955-A1 | HIGH LEVEL AMPLIFICATION AND EXPRESSION OF EXOGENOUS DNA | GENETICS INSTITUTE, INC. (US) | 1987-05-20 | — | — | EP | disclosed |
| WO-1987002707-A1 | MULTIPLY-AMPLIFIABLE VECTORS FOR HIGH LEVEL EXPRESSION OF EXOGENOUS DNA | GENETICS INSTITUTE, INC. (US) | 1987-05-07 | — | — | WO | disclosed |
| WO-1986006409-A1 | HIGH LEVEL AMPLIFICATION AND EXPRESSION OF EXOGENOUS DNA | GENETICS INSTITUTE, INC. (US) | 1986-11-06 | — | — | WO | disclosed |