Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Vidarabine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 known ✓ | P0DMS8 | 4/20 | 1.00 |
| ▸ | ADORA2A known ✓ | P29274 | 1/20 | 1.00 |
| ▸ | ADORA2B known ✓ | P29275 | 1/20 | 1.00 |
| ▸ | ADORA1 known ✓ | P30542 | 1/20 | 1.00 |
| ▸ | DPP4 | P27487 | 1/20 | 1.00 |
| ▸ | MEN1 | O00255 | 1/20 | 1.00 |
| ▸ | SLC28A1 | O00337 | 1/20 | 1.00 |
| ▸ | MAP3K7 | O43318 | 1/20 | 1.00 |
| ▸ | SLC28A2 | O43868 | 1/20 | 1.00 |
| ▸ | GAPDH | P04406 | 1/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 1/20 | 1.00 |
| ▸ | STAT6 | P42226 | 1/20 | 1.00 |
| ▸ | PI4KA | P42356 | 1/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 1/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 1.00 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 1.00 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 1.00 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 1.00 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 1.00 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adenosine SCHEMBL12352425 | 1.00 | ADORA3 (1.00) | ADORA3DPP4MEN1SLC28A1MAP3K7 | |
| Adenosine SCHEMBL1821276 | 1.00 | ADORA3 (1.00) | ADORA3DPP4MEN1SLC28A1MAP3K7 | |
| Adenosine SCHEMBL4522263 | 1.00 | ADORA3 (1.00) | ADORA3DPP4MEN1SLC28A1MAP3K7 | |
| Adenosine SCHEMBL13362239 | 1.00 | ADORA3 (1.00) | ADORA3DPP4MEN1SLC28A1MAP3K7 | |
| Adenosine SCHEMBL24538665 | 1.00 | ADORA3 (1.00) | ADORA3DPP4MEN1SLC28A1MAP3K7 | |
| Adenosine SCHEMBL2228590 | 1.00 | ADORA3 (1.00) | ADORA3DPP4MEN1SLC28A1MAP3K7 | |
| Adenosine SCHEMBL23804425 | 1.00 | ADORA3 (1.00) | ADORA3DPP4MEN1SLC28A1MAP3K7 | |
| Adenosine SCHEMBL406207 | 1.00 | ADORA3 (1.00) | ADORA3DPP4MEN1SLC28A1MAP3K7 | |
| Adenosine SCHEMBL23420216 | 1.00 | ADORA3 (1.00) | ADORA3DPP4MEN1SLC28A1MAP3K7 | |
| Adenosine SCHEMBL2403819 | 1.00 | ADORA3 (1.00) | ADORA3DPP4MEN1SLC28A1MAP3K7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 6502 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4398920-A1 | USE OF BACILLUS AMYLOLIQUEFACIENS FOR PREVENTING AND TREATING PARKINSON'S DISEASE | Artugen Therapeutics Ltd. (IE) | 2024-07-17 | — | — | EP | claimed |
| CN-112533923-B | Pyrazolopyrimidine compounds as adenosine receptor antagonists | 爱克思科技有限公司 | 2024-07-09 | — | — | CN | claimed |
| US-20240190909-A1 | SOLID FORMS OF (2S,3S,4S,5R,6S)-3,4,5-TRIHYDROXY-6-(((4AR,10AR)-7-HYDROXY-1-PROPYL-1,2,3,4,4A,5,10,10A-OCTAHYDROBENZO[G]QUINOLIN-6-YL)OXY)TETRAHYDRO-2H-PYRAN-2-CARBOXYLIC ACID | H. LUNDBECK A/S (DK) | 2024-06-13 | — | — | US | claimed |
| US-20240165081-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF INSOMNIA | HOFFMAN ABRAHAM J (US) | 2024-05-23 | — | — | US | claimed |
| CN-118019543-A | Use of bacillus amyloliquefaciens for preventing and treating parkinson's disease | 阿尔图根治疗有限公司 | 2024-05-10 | — | — | CN | claimed |
| US-20240108624-A1 | PYRAZOLOPYRIMIDINE COMPOUNDS AS ADENOSINE RECEPTOR ANTAGONISTS | EXSCIENTIA LTD., (GB) | 2024-04-04 | — | — | US | claimed |
| CN-117729937-A | Methods and compositions relating to adenosine receptors | 特韦斯特生物科学公司 | 2024-03-19 | — | — | CN | claimed |
| CN-117653649-A | Novel catecholamine prodrugs for the treatment of parkinson's disease | H.隆德贝克有限公司 | 2024-03-08 | — | — | CN | claimed |
| CN-117625724-A | Drug screening method taking gap connection function as target | 中国医学科学院药物研究所 | 2024-03-01 | — | — | CN | claimed |
| CN-117599073-A | Novel catecholamine prodrugs for the treatment of parkinson's disease | H.隆德贝克有限公司 | 2024-02-27 | — | — | CN | claimed |
| WO-1989012380-A2 | THERAPEUTIC USES OF 2',5'-OLIGOADENYLATE DERIVATIVES | TEMPLE UNIVERSITY OF THE COMMONWEALTH SYSTEM OF HI (US) | 1989-12-28 | — | — | WO | claimed |
| EP-0317728-A2 | Use of 9-(beta-D-arabinofuranosyl) adenine derivatives for the preparation of pharmaceutical compositions for the treatment of aids | WARNER-LAMBERT COMPANY (US) | 1989-05-31 | — | — | EP | claimed |
| EP-0156524-B1 | 2'-CHLOROPENTOSTATIN, A PHARMACEUTICAL COMPOSITION COMPRISING THE COMPOUND AND A NOVEL MICROORGANISM FOR PRODUCING THE COMPOUND | WARNER-LAMBERT COMPANY (US) | 1988-05-11 | — | — | EP | claimed |
| US-4713372-A | 2-chloropentostatin compound having adenosine diaminase inhibitory activity | WARNER-LAMBERT COMPANY (US) | 1987-12-15 | — | — | US | claimed |
| EP-0156524-A2 | 2'-Chloropentostatin, a pharmaceutical composition comprising the compound and a novel microorganism for producing the compound | WARNER-LAMBERT COMPANY (US) | 1985-10-02 | — | — | EP | claimed |
| EP-0106309-A2 | Biologically active extracts, process for their manufacture, medicinal and cosmetical preparations comprising them, and their use as additives in foodstuffs and stimulants | Gauri, Kailash Kumar, Dr. Prof. (DE) | 1984-04-25 | — | — | EP | claimed |
| EP-0079054-A1 | Enhancer of antitumor effect | Yamasa Shoyu Kabushiki Kaisha (JP) | 1983-05-18 | — | — | EP | claimed |
| US-4315920-A | Adenosine deaminase inhibitors | BURROUGHS WELLCOME CO. (US) | 1982-02-16 | — | — | US | claimed |
| US-4123609-A | PHOSPHORYLATION, HYDROLYSIS | WARNER-LAMBERT COMPANY (US) | 1978-10-31 | — | — | US | claimed |
| US-4055717-A | 9-(3-O-Acyl-β-D-arabinofuranosyl)adenine compounds, 9-(2,3-di-O-acyl-β-D-arabinofuranosyl)-adenine compounds, and method for their production | PARKE, DAVIS & COMPANY (US) | 1977-10-25 | — | — | US | claimed |