Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20290135 | 1.00 | KIF11 (0.44) | KIF11MEN1KMT2ANPC1RAB9A | |
| SCHEMBL20268404 | 0.85 | ADRA2A (0.43) | KIF11MEN1KMT2ANPC1RAB9A | |
| SCHEMBL20268402 | 0.85 | ADRA2A (0.43) | KIF11MEN1KMT2ANPC1RAB9A | |
| SCHEMBL2482093 | 0.82 | KIF11 (0.49) | KIF11MEN1KMT2ANPC1RAB9A | |
| SCHEMBL28091404 | 0.80 | KMT2A (0.52) | KIF11MEN1KMT2ANPC1RAB9A | |
| SCHEMBL20290131 | 0.78 | HDAC4 (0.44) | KIF11MEN1KMT2ANPC1RAB9A | |
| SCHEMBL3739537 | 0.74 | HDAC3 (0.50) | KIF11KMT2AMAPTHDAC3HDAC4 | |
| SCHEMBL20290768 | 0.73 | NR3C2 (0.39) | KIF11MEN1KMT2ANPC1RAB9A | |
| SCHEMBL20290132 | 0.73 | NR3C2 (0.39) | KIF11MEN1KMT2ANPC1RAB9A | |
| SCHEMBL25968736 | 0.73 | HDAC3 (0.44) | KIF11KMT2ANPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018109496-A2 | UNNATURAL AMINO ACIDS | THE UNIVERSITY OF BRISTOL (GB) | 2018-06-21 | — | — | WO | disclosed |