Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3636907 | 0.86 | MAPT (0.84) | MAPTSMN1; SMN2POLBPKMMGLL | |
| SCHEMBL9846293 | 0.82 | MAPT (0.46) | MAPTSMN1; SMN2POLBPKMMGLL | |
| SCHEMBL7508308 | 0.76 | POLB (0.49) | MAPTSMN1; SMN2POLBPKMCA12 | |
| SCHEMBL4124349 | 0.75 | — | — | |
| SCHEMBL1106494 | 0.74 | SMN1; SMN2 (0.46) | MAPTSMN1; SMN2POLBPKMCA12 | |
| SCHEMBL3131966 | 0.74 | MEN1 (0.58) | MAPTSMN1; SMN2POLBCA12CA1 | |
| SCHEMBL282864 | 0.73 | — | — | |
| SCHEMBL14260724 | 0.73 | MAPT (0.64) | MAPTSMN1; SMN2POLBPKMMGLL | |
| SCHEMBL25844476 | 0.72 | MAPT (0.62) | MAPTSMN1; SMN2POLBPKMMGLL | |
| SCHEMBL908027 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018109496-A2 | UNNATURAL AMINO ACIDS | THE UNIVERSITY OF BRISTOL (GB) | 2018-06-21 | — | — | WO | disclosed |