Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 19/20 | 0.59 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.57 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29781083 | 0.80 | NR1H2 (0.55) | NR1H2NR1H3CA12CA9 | |
| SCHEMBL7902953 | 0.80 | NR1H2 (0.55) | NR1H2NR1H3CA12CA9 | |
| SCHEMBL29524946 | 0.80 | NR1H2 (0.55) | NR1H2NR1H3CA12CA9 | |
| SCHEMBL4760328 | 0.80 | NR1H2 (0.68) | NR1H2NR1H3CA12CA9 | |
| SCHEMBL4251782 | 0.79 | NR1H2 (0.54) | NR1H2NR1H3CA12CA9 | |
| SCHEMBL3852059 | 0.79 | NR1H2 (0.57) | NR1H2NR1H3CA12CA9 | |
| SCHEMBL29725642 | 0.79 | NR1H2 (0.54) | NR1H2NR1H3CA12CA9 | |
| SCHEMBL18537881 | 0.78 | NR1H2 (0.53) | NR1H2NR1H3CA12CA9 | |
| SCHEMBL5677101 | 0.78 | NR1H2 (0.59) | NR1H2NR1H3CA12CA9 | |
| SCHEMBL24894603 | 0.78 | NOD2 (0.62) | NR1H2NR1H3CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107406431-B | Indole derivatives, preparation method and medical application thereof | 上海昂睿医药技术有限公司 | 2020-06-26 | — | — | CN | disclosed |
| US-20180194751-A1 | INDOLE DERIVATIVE, PREPARATION METHOD THEREOF, AND USE THEREOF IN PHARMACEUTICAL DRUG | ZHEJIANG HISUN PHARMACEUTICAL CO., LTD. (CN) | 2018-07-12 | — | — | US | disclosed |
| EP-3339305-A1 | INDOLE DERIVATIVE, PREPARATION METHOD THEREOF, AND USE THEREOF IN PHARMACEUTICAL DRUG | Zhejiang Hisun Pharmaceutical Co., Ltd (CN) | 2018-06-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180194751-A1 | INDOLE DERIVATIVE, PREPARATION METHOD THEREOF, AND USE THEREOF IN PHARMACEUTICAL DRUG | FGFR1, FGFR2, FGFR4 | NR1H2 2721/4885NR1H3 2768/4885CA12 4196/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.