Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.36 |
| ▸ | CCR6 | P51684 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 3/20 | 0.36 |
| ▸ | CNR1 | P21554 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1133675 | 1.00 | ALDH1A1 (0.42) | ALDH1A1HPGDHTTSMN1; SMN2CYP1A2 | |
| SCHEMBL30434850 | 0.82 | IDO1 (0.60) | ALDH1A1HPGDHTTSMN1; SMN2KDM4E | |
| SCHEMBL149947 | 0.82 | IDO1 (0.60) | ALDH1A1HPGDHTTSMN1; SMN2KDM4E | |
| SCHEMBL5661861 | 0.81 | ALDH1A1 (0.46) | ALDH1A1HPGDHTTSMN1; SMN2CYP1A2 | |
| SCHEMBL12580912 | 0.81 | ALDH1A1 (0.41) | ALDH1A1HPGDHTTSMN1; SMN2KDM4E | |
| SCHEMBL9570558 | 0.79 | ALDH1A1 (0.53) | ALDH1A1HPGDHTTSMN1; SMN2MEN1 | |
| SCHEMBL8050760 | 0.77 | IDO1 (0.50) | ALDH1A1HPGDHTTSMN1; SMN2KDM4E | |
| SCHEMBL2651404 | 0.76 | ALDH1A1 (0.50) | ALDH1A1HPGDHTTSMN1; SMN2MEN1 | |
| SCHEMBL10457902 | 0.76 | ALDH1A1 (0.50) | ALDH1A1HPGDHTTSMN1; SMN2MEN1 | |
| SCHEMBL2650270 | 0.76 | ALDH1A1 (0.50) | ALDH1A1HPGDHTTSMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110130557-A1 | INTERCALATING TRIPLEXES AND DUPLEXES USING ARYL NAPHTHOIMIDAZOL AND PROCESS FOR THE PREPARATION THEREOF | SYDDANSK UNIVERSITET (DK) | 2011-06-02 | — | — | US | disclosed |
| US-20110130557-A1 | INTERCALATING TRIPLEXES AND DUPLEXES USING ARYL NAPHTHOIMIDAZOL AND PROCESS FOR THE PREPARATION THEREOF | SYDDANSK UNIVERSITET (DK) | 2011-06-02 | — | — | US | disclosed |
| US-20110130557-A1 | INTERCALATING TRIPLEXES AND DUPLEXES USING ARYL NAPHTHOIMIDAZOL AND PROCESS FOR THE PREPARATION THEREOF | SYDDANSK UNIVERSITET (DK) | 2011-06-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110130557-A1 | INTERCALATING TRIPLEXES AND DUPLEXES USING ARYL NAPHTHOIMIDAZOL AND PROCESS FOR THE PREPARATION THEREOF | POLRMT, DDX1, DDX18 | ALDH1A1 1439/4885HPGD 3801/4885HTT 933/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.