Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 5/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL342646 | 1.00 | CA1 (0.38) | CA1CES2CES1EPHX1NPC1 | |
| Acetic Acid SCHEMBL4881564 | 0.85 | CES2 (0.38) | CES2CES1EPHX1NPC1RAB9A | |
| Acetic Acid SCHEMBL3009445 | 0.83 | CES2 (0.36) | CES2CES1EPHX1NPC1RAB9A | |
| Acetic Acid SCHEMBL2465122 | 0.83 | CES2 (0.36) | CES2CES1EPHX1NPC1RAB9A | |
| Acetic Acid SCHEMBL3009441 | 0.83 | CES2 (0.36) | CES2CES1EPHX1NPC1RAB9A | |
| Acetic Acid SCHEMBL1450786 | 0.82 | EPHX1 (0.34) | EPHX1 | |
| Trifluoroacetic Acid SCHEMBL3184978 | 0.80 | CES2 (0.31) | CES2CES1 | |
| Trifluoroacetic Acid SCHEMBL3181588 | 0.80 | CES2 (0.31) | CES2CES1 | |
| Trifluoroacetic Acid SCHEMBL3181321 | 0.80 | CES2 (0.31) | CES2CES1 | |
| Trifluoroacetic Acid SCHEMBL3165098 | 0.80 | CES2 (0.31) | CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 101 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250353943-A1 | FAST PHOTOCURABLE POLYCYCLOOLEFIN COMPOSITIONS AS OPTICAL OR 3D PRINTING MATERIALS | PROMERUS, LLC (US) | 2025-11-20 | — | — | US | claimed |
| US-12391775-B2 | Fast photocurable polycycloolefin compositions as optical or 3D printing materials | PROMERUS, LLC (US) | 2025-08-19 | — | — | US | claimed |
| EP-3565850-B1 | POLYCYCLOOLEFIN POLYMER COMPOSITIONS AS OPTICAL MATERIALS | PROMERUS LLC (US) | 2025-07-23 | — | — | EP | claimed |
| EP-4584309-A1 | POLYCYCLIC-OLEFINIC POLYMERS CONTAINING ACRYLATE FUNCTIONALITY WITH ACRYLATE/MALEIMIDE CROSSLINKERS AS B-STAGEABLE COMPOSITIONS FOR LOW LOSS APPLICATIONS | Promerus, LLC (US) | 2025-07-16 | — | — | EP | claimed |
| CN-119968406-A | Polycyclic olefin polymers containing acrylate functionality and acrylate/maleimide crosslinkers as B-stageable compositions in low loss applications | 普罗米鲁斯有限责任公司 | 2025-05-09 | — | — | CN | claimed |
| US-12180385-B2 | Shelf life stable and improved mass polymerizable polycyclic-olefinic compositions | PROMERYS, LLC (US) | 2024-12-31 | — | — | US | claimed |
| WO-2024054548-A1 | POLYCYCLIC-OLEFINIC POLYMERS CONTAINING ACRYLATE FUNCTIONALITY WITH ACRYLATE/MALEIMIDE CROSSLINKERS AS B-STAGEABLE COMPOSITIONS FOR LOW LOSS APPLICATIONS | PROMERUS, LLC (US) | 2024-03-14 | — | — | WO | claimed |
| US-11845880-B2 | Polycyclic-olefinic compositions for low-loss films having improved thermal properties | PROMERUS, LLC (US) | 2023-12-19 | — | — | US | claimed |
| EP-4237460-A1 | POLYCYCLIC-OLEFINIC COMPOSITIONS FOR LOW-LOSS FILMS HAVING IMPROVED THERMAL PROPERTIES | Promerus, LLC (US) | 2023-09-06 | — | — | EP | claimed |
| EP-4237461-A1 | SHELF LIFE STABLE AND IMPROVED MASS POLYMERIZABLE POLYCYCLIC-OLEFINIC COMPOSITIONS | Promerus, LLC (US) | 2023-09-06 | — | — | EP | claimed |
| US-20230220132-A1 | FAST PHOTOCURABLE POLYCYCLOOLEFIN COMPOSITIONS AS OPTICAL OR 3D PRINTING MATERIALS | PROMERUS, LLC (US) | 2023-07-13 | — | — | US | claimed |
| CN-116368165-A | Polycyclic olefin composition for low loss films with improved thermal properties | 普罗米鲁斯有限责任公司 | 2023-06-30 | — | — | CN | claimed |
| WO-2022094236-A1 | SHELF LIFE STABLE AND IMPROVED MASS POLYMERIZABLE POLYCYCLIC-OLEFINIC COMPOSITIONS | PROMERUS, LLC (US) | 2022-05-05 | — | — | WO | claimed |
| US-20220135831-A1 | POLYCYCLIC-OLEFINIC COMPOSITIONS FOR LOW-LOSS FILMS HAVING IMPROVED THERMAL PROPERTIES | PROMERUS, LLC (US) | 2022-05-05 | — | — | US | claimed |
| US-20220135832-A1 | SHELF LIFE STABLE AND IMPROVED MASS POLYMERIZABLE POLYCYCLIC-OLEFINIC COMPOSITIONS | PROMERUS, LLC (US) | 2022-05-05 | — | — | US | claimed |
| WO-2022094232-A1 | POLYCYCLIC-OLEFINIC COMPOSITIONS FOR LOW-LOSS FILMS HAVING IMPROVED THERMAL PROPERTIES | PROMERUS, LLC (US) | 2022-05-05 | — | — | WO | claimed |
| US-20260055268-A1 | HALOGEN FREE AND PHOSPHORUS FREE LOW LOSS FLAME RETARDANT COMPOSITIONS CONTAINING POLYCYCLIC-OLEFINIC POLYMER WITH OLEFINIC FUNCTIONALITY AND MELAMINE | PROMERUS, LLC (US) | 2026-02-26 | — | — | US | disclosed |
| US-20250388745-A1 | HALOGEN FREE AND PHOSPHORUS FREE LOW LOSS FLAME RETARDANT COMPOSITIONS CONTAINING POLYCYCLIC-OLEFINIC POLYMER WITH OLEFINIC FUNCTIONALITY, MELAMINE AND CLAY | PROMERUS, LLC (US) | 2025-12-25 | — | — | US | disclosed |
| WO-2006023511-A1 | POLYCYCLOOLEFIN POLYMERIC COMPOSITIONS FOR SEMICONDUCTOR APPLICATIONS | PROMERUS LLC (US) | 2006-03-02 | — | — | WO | disclosed |
| US-20060041093-A1 | Polycycloolefin polymeric compositions for semiconductor applications | SUMITOMO BAKELITE CO., LTD. (JP) | 2006-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260055268-A1 | HALOGEN FREE AND PHOSPHORUS FREE LOW LOSS FLAME RETARDANT COMPOSITIONS CONTAINING POLYCYCLIC-OLEFINIC POLYMER WITH OLEFINIC FUNCTIONALITY AND MELAMINE | RAD52, PYM1, MCM4 | CA1 1309/4885CES2 3486/4885CES1 4329/4885 |
| US-20250388745-A1 | HALOGEN FREE AND PHOSPHORUS FREE LOW LOSS FLAME RETARDANT COMPOSITIONS CONTAINING POLYCYCLIC-OLEFINIC POLYMER WITH OLEFINIC FUNCTIONALITY, MELAMINE AND CLAY | PYM1, MCM4, MELK | CA1 975/4885CES2 3517/4885CES1 4260/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.