Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 5/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL202979 | 1.00 | CA1 (0.38) | CA1CES2CES1EPHX1NPC1 | |
| Acetic Acid SCHEMBL4881564 | 0.85 | CES2 (0.38) | CES2CES1EPHX1NPC1RAB9A | |
| Acetic Acid SCHEMBL3009445 | 0.83 | CES2 (0.36) | CES2CES1EPHX1NPC1RAB9A | |
| Acetic Acid SCHEMBL2465122 | 0.83 | CES2 (0.36) | CES2CES1EPHX1NPC1RAB9A | |
| Acetic Acid SCHEMBL3009441 | 0.83 | CES2 (0.36) | CES2CES1EPHX1NPC1RAB9A | |
| Acetic Acid SCHEMBL1450786 | 0.82 | EPHX1 (0.34) | EPHX1 | |
| Trifluoroacetic Acid SCHEMBL3184978 | 0.80 | CES2 (0.31) | CES2CES1 | |
| Trifluoroacetic Acid SCHEMBL3181588 | 0.80 | CES2 (0.31) | CES2CES1 | |
| Trifluoroacetic Acid SCHEMBL3181321 | 0.80 | CES2 (0.31) | CES2CES1 | |
| Trifluoroacetic Acid SCHEMBL3165098 | 0.80 | CES2 (0.31) | CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025103220-A1 | PYRIDYL ALKOXY PYRIMIDINE COMPOUND AND USE THEREOF | 青岛清原化合物有限公司 | 2025-05-22 | — | — | WO | claimed |
| CN-120004854-A | Pyridylalkoxypyrimidine class compound and application thereof | 青岛清原化合物有限公司 | 2025-05-16 | — | — | CN | claimed |
| CN-118324770-A | Cyclic compound based on 1-aryl carbazole unit, and preparation method and application thereof | 中国石油化工股份有限公司 | 2024-07-12 | — | — | CN | claimed |
| CN-112538049-A | Blue fluorescent material with high exciton utilization rate and preparation and application thereof | 华南理工大学 | 2021-03-23 | — | — | CN | claimed |
| WO-2025103220-A1 | PYRIDYL ALKOXY PYRIMIDINE COMPOUND AND USE THEREOF | 青岛清原化合物有限公司 | 2025-05-22 | — | — | WO | disclosed |
| CN-120004854-A | Pyridylalkoxypyrimidine class compound and application thereof | 青岛清原化合物有限公司 | 2025-05-16 | — | — | CN | disclosed |
| CN-118324770-A | Cyclic compound based on 1-aryl carbazole unit, and preparation method and application thereof | 中国石油化工股份有限公司 | 2024-07-12 | — | — | CN | disclosed |
| CN-112538049-B | Blue fluorescent material with high exciton utilization rate and preparation and application thereof | 华南理工大学 | 2022-12-16 | — | — | CN | disclosed |
| CN-110803973-B | Method for reducing carboxylic acid into aldehyde compound | 郑州大学 | 2022-05-17 | — | — | CN | disclosed |
| CN-112538049-A | Blue fluorescent material with high exciton utilization rate and preparation and application thereof | 华南理工大学 | 2021-03-23 | — | — | CN | disclosed |
| CN-110803973-A | Method for reducing carboxylic acid into aldehyde compound | 郑州大学 | 2020-02-18 | — | — | CN | disclosed |
| CN-107987256-B | red heat-induced delayed fluorescence polymer and preparation and application thereof | 中国科学院长春应用化学研究所 | 2020-01-31 | — | — | CN | disclosed |
| US-20120014909-A1 | TISSUE ADHESIVE AND SEALANT COMPRISING POLYGLYCEROL ALDEHYDE | ACTAMAX SURGICAL MATERIALS, LLC (US) | 2012-01-19 | — | — | US | disclosed |
| US-8013172-B2 | Cycloalkylphenyl substituted cyclic ketoenols | BAYER CROPSCIENCE AG (DE) | 2011-09-06 | — | — | US | disclosed |
| US-20090305891-A1 | CYCLOALKYLPHENYL SUBSTITUTED CYCLIC KETOENOLS | BAYER CROPSCIENCE AG (DE) | 2009-12-10 | — | — | US | disclosed |
| WO-2009088103-A1 | PYRIDYLAMIDINE COMPOUND OR SALT THEREOF, AND AGRICULTURAL OR HORTICULTURAL FUNGICIDE COMPOSITION CONTAINING THE SAME AS ACTIVE INGREDIENT | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2009-07-16 | — | — | WO | disclosed |
| US-7557103-B2 | Imidazopyridazine compounds | ELI LILLY AND COMPANY (US) | 2009-07-07 | — | — | US | disclosed |
| US-20080153828-A1 | Imidazopyridazine Compounds | ELI LILLY AND COMPANY | 2008-06-26 | — | — | US | disclosed |
| EP-1879896-A1 | IMIDAZOPYRIDAZINE COMPOUNDS | ELI LILLY AND COMPANY (US) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006107784-A1 | IMIDAZOPYRIDAZINE COMPOUNDS | ELI LILLY AND COMPANY (US) | 2006-10-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080153828-A1 | Imidazopyridazine Compounds | CRHR1, CRH, CRHR2 | CA1 2431/4885CES2 2581/4885CES1 1615/4885 |
| US-20090305891-A1 | CYCLOALKYLPHENYL SUBSTITUTED CYCLIC KETOENOLS | PHYKPL, KCNE1, PKM | CA1 1167/4885CES2 453/4885CES1 472/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.