Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 5/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | ATR | Q13535 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 6/20 | 0.32 |
| ▸ | LMNA | P02545 | 5/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2034278 | 0.87 | MAPT (0.41) | CYP1A2TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL2035185 | 0.86 | CYP1A2 (0.39) | CYP1A2TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL5583271 | 0.85 | CYP1A2 (0.48) | CYP1A2TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL5583275 | 0.83 | MAPT (0.41) | CYP1A2TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL2034251 | 0.83 | MEN1 (0.36) | CYP1A2TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL2035326 | 0.81 | MAPT (0.49) | CYP1A2ALDH1A1KMT2AMAPTLMNA | |
| SCHEMBL2028883 | 0.81 | LMNA (0.45) | TSHRALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL5583481 | 0.79 | TSHR (0.40) | CYP1A2TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL5583455 | 0.79 | HCAR3 (0.41) | CYP1A2TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL2029343 | 0.77 | MAPT (0.46) | ALDH1A1MEN1KMT2ATDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7956011-B2 | Materials and methods for the photodirected synthesis of oligonucleotide arrays | THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL (GB) | 2011-06-07 | — | — | US | claimed |
| US-7956011-B2 | Materials and methods for the photodirected synthesis of oligonucleotide arrays | THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL (GB) | 2011-06-07 | — | — | US | disclosed |
| US-20090270279-A1 | Materials and Methods for the Photodirected Synthesis of Oligonucleotide Arrays | THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL (GB) | 2009-10-29 | — | — | US | disclosed |