SCHEMBL20299286

SCHEMBL20299286

CC(=O)Nc1cc(S(=O)(=O)O)cc2cc(S(=O)(=O)O)ccc12

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CASP6 P55212 4/20 0.74
PRMT1 Q99873 1/20 0.52
NSD2 O96028 1/20 0.45
DUSP3 P51452 1/20 0.45
PTPN5 P54829 1/20 0.45
PTPN11 Q06124 1/20 0.45
CA2 P00918 6/20 0.44
CA1 P00915 5/20 0.44
CA9 Q16790 4/20 0.44
CTDSP1 Q9GZU7 1/20 0.44
ALDH1A1 P00352 3/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2C19 P33261 1/20 0.44
HSD17B10 Q99714 1/20 0.44
APEX1 P27695 1/20 0.44
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
CASR P41180 1/20 0.43
CA3 P07451 1/20 0.43
KDM4E B2RXH2 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10900256 0.87 PRMT1 (0.63) CASP6PRMT1NSD2DUSP3PTPN5
SCHEMBL16328859 0.86 CASP6 (0.56) CASP6PRMT1NSD2DUSP3PTPN5
SCHEMBL8018981 0.86 CASP6 (0.72) CASP6NSD2DUSP3PTPN5PTPN11
SCHEMBL11436880 0.85 CASP6 (0.56) CASP6PRMT1NSD2DUSP3PTPN5
SCHEMBL7225514 0.85 CASP6 (1.00) CASP6PRMT1CA2CA1CA9
SCHEMBL3895105 0.84 NT5E (0.56) CASP6PRMT1NSD2DUSP3PTPN5
SCHEMBL4107132 0.84 CASP6 (0.97) CASP6PRMT1CA2CA1CA9
SCHEMBL3895091 0.83 NT5E (0.55) CASP6PRMT1NSD2DUSP3PTPN5
SCHEMBL11311222 0.82 CASP6 (0.52) CASP6PRMT1NSD2DUSP3PTPN5
SCHEMBL8367846 0.81 CASP6 (0.68) CASP6PRMT1NSD2CA2CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230139146-A1 DYEING OR LIGHTENING PROCESS USING A HAND-HELD STYLING DEVICE AND A SUBSTRATE L'OREAL (FR) 2023-05-04 US disclosed
EP-3558462-A1 PROCESS FOR DYEING AND RELAXING CURLS OF KERATIN FIBRES, USING REDUCING AGENTS AND HAIR DYES, AND ASSOCIATED KIT L'Oreal (FR) 2019-10-30 EP disclosed
WO-2018115393-A1 PROCESS FOR DYEING AND RELAXING CURLS OF KERATIN FIBRES, USING REDUCING AGENTS AND HAIR DYES, AND ASSOCIATED KIT L'OREAL (FR) 2018-06-28 WO disclosed
WO-2018115450-A1 PROCESS FOR DIRECT DYEING OF KERATIN FIBRES COMPRISING THE APPLICATION OF TWO PARTICULAR COMPOSITIONS L'OREAL (FR) 2018-06-28 WO disclosed
WO-2018115451-A1 COSMETIC COMPOSITION FOR DIRECT DYEING COMPRISING AN AQUEOUS PHASE AND A FATTY PHASE THAT ARE VISUALLY DISTINCT FROM EACH OTHER L'OREAL (FR) 2018-06-28 WO disclosed
WO-2018115059-A1 PROCESS FOR DYEING KERATIN FIBRES USING A COMPOSITION COMPRISING AT LEAST TWO ORGANOSILANES DIFFERENT FROM ONE ANOTHER L'OREAL (FR) 2018-06-28 WO disclosed
CN-1286618-A Keratinous fibre oxidation dyeing composition contg. laccase and dyeing method using same OREAL (FR) 2001-03-07 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230139146-A1 DYEING OR LIGHTENING PROCESS USING A HAND-HELD STYLING DEVICE AND A SUBSTRATE KRT18, TPM3, PRKDC CASP6 1056/4885PRMT1 589/4885NSD2 1011/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.