Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP6 | P55212 | 1/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | RHOA | P61586 | 1/20 | 0.52 |
| ▸ | FGF1 | P05230 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4107132 | 0.99 | CASP6 (0.97) | CASP6KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL4102145 | 0.88 | CASP6 (0.79) | CASP6KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL4103361 | 0.87 | CASP6 (0.77) | CASP6KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL4107129 | 0.87 | CASP6 (0.77) | CASP6KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL4486332 | 0.87 | CASP6 (0.77) | CASP6KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL7231212 | 0.86 | CASP6 (0.75) | CASP6KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL11214034 | 0.86 | CASP6 (0.76) | CASP6KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL10626847 | 0.86 | CASP6 (0.76) | CASP6KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL20299286 | 0.85 | CASP6 (0.74) | CASP6KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL26885732 | 0.85 | CASP6 (0.73) | CASP6KDM4EALDH1A1RHOAFGF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4908478-A | Single-vessel process for preparing 2-acetaminonaphthalene-6-sulfonic acid of high purity | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-03-13 | — | — | US | claimed |
| US-20230381159-A1 | SMALL MOLECULE INHIBITORS OF CORONAVIRUS ATTACHMENT AND ENTRY, METHODS AND USES THEREOF | UNIVERSITY OF MIAMI | 2023-11-30 | — | — | US | disclosed |
| US-6653321-B1 | Stimulating kinase activity of insulin receptor; type II diabetes; hyperglycemia | TELIK, INC. | 2003-11-25 | — | — | US | disclosed |
| EP-1200396-A1 | NAPHTHYLSULFONIC ACIDS AND RELATED COMPOUNDS AS GLUCOSE UPTAKE AGONISTS | TELIK, INC. (US) | 2002-05-02 | — | — | EP | disclosed |
| WO-2001012591-A1 | NOVEL NAPHTHYLSULFONIC ACIDS AND RELATED COMPOUNDS AS GLUCOSE UPTAKE AGONISTS | TELIK, INC. (US) | 2001-02-22 | — | — | WO | disclosed |
| EP-0555699-B1 | Process for the preparation of aminourethanes | BAYER AG (DE) | 1998-01-07 | — | — | EP | disclosed |
| EP-0555699-A2 | Aromatic compounds substituted by an urethane group and by an amino group | BAYER AG (DE) | 1993-08-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230381159-A1 | SMALL MOLECULE INHIBITORS OF CORONAVIRUS ATTACHMENT AND ENTRY, METHODS AND USES THEREOF | ACE2, ACE, SARS1 | CASP6 2657/4885KDM4E 3581/4885ALDH1A1 2115/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.