Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 1/20 | 0.49 |
| ▸ | TUBB | P07437 | 1/20 | 0.49 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.49 |
| ▸ | AR | P10275 | 1/20 | 0.49 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.49 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.49 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.49 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.49 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.49 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.49 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.49 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.49 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.49 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.49 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.49 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.47 |
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | MEN1 | O00255 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20320053 | 0.79 | HDAC3 (0.47) | TUBB4ATUBBTUBA3CARTUBA1B | |
| SCHEMBL895414 | 0.77 | UNG (0.56) | KMT2AMAPTALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL29451792 | 0.76 | HSD17B10 (0.41) | KMT2AMAPTMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL15496946 | 0.76 | SLC7A5 (0.48) | MAPTALDH1A1SMN1; SMN2TDP1SLC7A5 | |
| SCHEMBL18015981 | 0.76 | PTPRC (0.59) | MAPTALDH1A1L3MBTL1SMN1; SMN2SLC7A5 | |
| SCHEMBL31487534 | 0.76 | SLC7A5 (0.48) | MAPTALDH1A1SMN1; SMN2TDP1SLC7A5 | |
| SCHEMBL110296 | 0.74 | SLC7A5 (0.58) | ALDH1A1L3MBTL1TDP1SLC7A5 | |
| SCHEMBL20299514 | 0.74 | TUBB4A (0.84) | TUBB4ATUBBTUBA3CARTUBA1B | |
| SCHEMBL30390191 | 0.73 | KMT2A (0.50) | KMT2AMAPTMEN1L3MBTL1SMN1; SMN2 | |
| Water SCHEMBL28897664 | 0.73 | SLC7A5 (0.56) | ALDH1A1L3MBTL1TDP1SLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018114965-A1 | CLPX INHIBITORY COMPOUNDS FOR THE TREATMENT OF MULTI RESISTANT STAPHYLOCOCCUS AUREUS VIRULENCE AND FOR THE TREATMENT OF LEUKEMIA | Technische Universität München (DE) | 2018-06-28 | — | — | WO | disclosed |