SCHEMBL20299808

SCHEMBL20299808

COC(CCCCc1ccc(C(=O)c2ccccc2)cc1)(C(=O)c1ccccc1)C(=O)c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARG P37231 4/20 0.48
ATM Q13315 1/20 0.44
PPARA Q07869 2/20 0.42
SRD5A2 P31213 1/20 0.42
HDAC1 Q13547 1/20 0.41
CYP4F2 P78329 1/20 0.41
CYP4A11 Q02928 1/20 0.41
CES1 P23141 1/20 0.41
ALDH1A1 P00352 2/20 0.41
HTT P42858 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
PPARD Q03181 1/20 0.41
MEN1 O00255 1/20 0.41
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
KMT2A Q03164 1/20 0.41
MLYCD O95822 1/20 0.40
GLI1 P08151 1/20 0.40
GLI2 P10070 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzophenone SCHEMBL2843986 0.83 CES1 (0.45) PPARACES1ALDH1A1L3MBTL1RAB9A
SCHEMBL4591841 0.80 CES1 (0.47) CES1
SCHEMBL31328399 0.80 CES1 (0.47) PPARACYP4F2CYP4A11CES1L3MBTL1
SCHEMBL8083975 0.79 CES1 (0.47) CES1
SCHEMBL15651 0.78 CES1 (0.49) CES1L3MBTL1KMT2A
SCHEMBL28251464 0.77 HDAC1 (0.62) PPARGSRD5A2HDAC1ALDH1A1MEN1
SCHEMBL2124071 0.77 CES1 (0.47) PPARACES1ALDH1A1L3MBTL1NPC1
Methane SCHEMBL16506198 0.77 CES1 (0.47) CES1L3MBTL1KMT2A
Water SCHEMBL28127793 0.77 CES1 (0.47) CES1L3MBTL1KMT2A
SCHEMBL11227652 0.75 RARB (0.65) ALDH1A1MEN1NPC1RAB9AKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110312551-B Cosmetic composition containing royal jelly of wasp's black bee LVMH研究公司 2022-05-13 CN disclosed
US-11020342-B2 Cosmetic composition comprising royal jelly of the Ouessant black bee L V M H RECHERCHE (FR) 2021-06-01 US disclosed
EP-3558468-B1 COSMETIC COMPOSITION COMPRISING ROYAL JELLY OF THE OUESSANT BLACK BEE LVMH RECH (FR) 2021-01-27 EP disclosed
EP-3558468-A1 COSMETIC COMPOSITION COMPRISING ROYAL JELLY OF THE OUESSANT BLACK BEE LVMH Recherche (FR) 2019-10-30 EP disclosed
WO-2018115487-A1 COSMETIC COMPOSITION COMPRISING AN ALBIZZIA JULIBRISSIN EXTRACT, A ROSEMARY EXTRACT AND ROYAL JELLY L V M H RECHERCHE (FR) 2018-06-28 WO disclosed
WO-2018115448-A1 COSMETIC COMPOSITION COMPRISING ROYAL JELLY OF THE OUESSANT BLACK BEE L V M H RECHERCHE (FR) 2018-06-28 WO disclosed