SCHEMBL2124071

SCHEMBL2124071

[CH2]CCCC(OC)(C(=O)c1ccccc1)C(=O)c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES1 P23141 3/20 0.47
SRC P12931 1/20 0.44
TSHR P16473 2/20 0.39
TDP1 Q9NUW8 4/20 0.36
LMNA P02545 3/20 0.36
POLB P06746 2/20 0.36
PPARA Q07869 1/20 0.35
MAPK1 P28482 1/20 0.35
HIF1A Q16665 1/20 0.35
CES2 O00748 1/20 0.35
AKT1 P31749 1/20 0.35
KMT2A Q03164 1/20 0.35
L3MBTL1 Q9Y468 3/20 0.35
MAPT P10636 4/20 0.35
ALDH1A1 P00352 3/20 0.35
HSD17B10 Q99714 1/20 0.34
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34
PAX8 Q06710 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15651 0.85 CES1 (0.49) CES1SRCTSHRTDP1LMNA
Methane SCHEMBL16506198 0.84 CES1 (0.47) CES1SRCTSHRTDP1LMNA
Water SCHEMBL28127793 0.84 CES1 (0.47) CES1SRCTSHRTDP1LMNA
SCHEMBL4591841 0.84 CES1 (0.47) CES1SRCLMNACES2
SCHEMBL31328399 0.84 CES1 (0.47) CES1SRCTSHRTDP1LMNA
SCHEMBL8083975 0.83 CES1 (0.47) CES1SRCTSHRCES2
Benzophenone SCHEMBL2843986 0.81 CES1 (0.45) CES1SRCTDP1LMNAPPARA
Dibenzoylmethane SCHEMBL2905077 0.79 KMT2A (0.49) CES1SRCTDP1LMNAMAPK1
Pyrrole SCHEMBL27588201 0.79 CES1 (0.43) CES1SRCTSHRTDP1LMNA
SCHEMBL20299808 0.77 PPARG (0.48) CES1PPARAKMT2AL3MBTL1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114449990-A UV resistant cosmetic composition 可泰克斯公司 2022-05-06 CN claimed
CN-114555049-A Water-repellent and/or light-protective composition comprising a non-solubilising micronized wax 路博润先进材料公司 2022-05-27 CN disclosed
CN-114449990-A UV resistant cosmetic composition 可泰克斯公司 2022-05-06 CN disclosed
US-10813856-B2 Physical solar filter consisting of substituted hydroxyapatite in an organic matrix CONSIGLIO NAZIONALE DELLE RICERCHE (IT) 2020-10-27 US disclosed
EP-3426224-B1 PHYSICAL SOLAR FILTER CONSISTING OF SUBSTITUTED HYDROXYAPATITE IN AN ORGANIC MATRIX CONSIGLIO NAZIONALE RICERCHE (IT) 2020-04-29 EP disclosed
US-20190070079-A1 PHYSICAL SOLAR FILTER CONSISTING OF SUBSTITUTED HYDROXYAPATITE IN AN ORGANIC MATRIX CONSIGLIO NAZIONALE DELLE RICERCHE (IT) 2019-03-07 US disclosed
EP-3426224-A1 PHYSICAL SOLAR FILTER CONSISTING OF SUBSTITUTED HYDROXYAPATITE IN AN ORGANIC MATRIX Consiglio Nazionale delle Ricerche (IT) 2019-01-16 EP disclosed
CN-109069365-A The physics solar energy filter being made of the substituted hydroxyapatite in organic substrate 意大利国家研究委员会 2018-12-21 CN disclosed
WO-2017153888-A1 PHYSICAL SOLAR FILTER CONSISTING OF SUBSTITUTED HYDROXYAPATITE IN AN ORGANIC MATRIX CONSIGLIO NAZIONALE DELLE RICERCHE (IT) 2017-09-14 WO disclosed
EP-2444396-A1 PHOTOPROTECTIVE COMPOSITION Apoteknos Para La Piel, S.L. (ES) 2012-04-25 EP disclosed