Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 10/20 | 0.45 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 8/20 | 0.36 |
| ▸ | NPC1 | O15118 | 7/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20300817 | 0.89 | AR (0.48) | ARPDE10ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL15560843 | 0.87 | PDE10A (0.40) | ARPDE10ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL20300706 | 0.82 | KDM4E (0.33) | ARPDE10AKDM4E | |
| SCHEMBL20300688 | 0.80 | AR (0.49) | ARRAB9ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL20300989 | 0.80 | ACP1 (0.39) | ARRAB9ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL20301063 | 0.79 | AR (0.45) | ARRAB9ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL20301037 | 0.79 | RAB9A (0.38) | ARRAB9ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL20301474 | 0.78 | NPC1 (0.40) | ARPDE10ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL20300671 | 0.78 | AR (0.43) | ARPDE10ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL20301463 | 0.77 | BACE1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018116072-A1 | HETEROCYCLIC COMPOUNDS | PI INDUSTRIES LTD. (IN) | 2018-06-28 | — | — | WO | claimed |
| WO-2018116072-A1 | HETEROCYCLIC COMPOUNDS | PI INDUSTRIES LTD. (IN) | 2018-06-28 | — | — | WO | disclosed |