Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 6/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | USP1 | O94782 | 3/20 | 0.31 |
| ▸ | WDR48 | Q8TAF3 | 3/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MPL | P40238 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20301006 | 0.90 | HSD11B1 (0.37) | HSD11B1CYP1A2CYP2D6CLK4CYP2C19 | |
| SCHEMBL20301138 | 0.89 | HSD11B1 (0.37) | HSD11B1CYP1A2CYP2D6CLK4CYP2C19 | |
| SCHEMBL20300999 | 0.89 | HSD11B1 (0.31) | HSD11B1 | |
| SCHEMBL20301404 | 0.87 | MGAM (0.31) | HSD11B1 | |
| SCHEMBL20300971 | 0.86 | PDE2A (0.30) | — | |
| SCHEMBL20300877 | 0.84 | — | — | |
| SCHEMBL20300902 | 0.82 | HSD11B1 (0.34) | HSD11B1CYP1A2CYP2D6CLK4CYP2C19 | |
| SCHEMBL20300883 | 0.81 | HSD11B1 (0.33) | HSD11B1CYP1A2CYP2D6CLK4CYP2C19 | |
| SCHEMBL20300899 | 0.81 | PDE2A (0.31) | HSD11B1 | |
| SCHEMBL20300863 | 0.80 | HSD11B1 (0.38) | HSD11B1MPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018116072-A1 | HETEROCYCLIC COMPOUNDS | PI INDUSTRIES LTD. (IN) | 2018-06-28 | — | — | WO | claimed |
| WO-2018116072-A1 | HETEROCYCLIC COMPOUNDS | PI INDUSTRIES LTD. (IN) | 2018-06-28 | — | — | WO | disclosed |