Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SI | P14410 | 1/20 | 0.31 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20300999 | 0.91 | HSD11B1 (0.31) | HSD11B1 | |
| SCHEMBL20301185 | 0.90 | PDE2A (0.32) | MGAMGAASIMGAM2 | |
| SCHEMBL20301395 | 0.88 | GAA (0.34) | MGAMGAASIMGAM2 | |
| SCHEMBL20300971 | 0.88 | PDE2A (0.30) | — | |
| SCHEMBL20301341 | 0.87 | HSD11B1 (0.38) | HSD11B1 | |
| SCHEMBL20300877 | 0.86 | — | — | |
| SCHEMBL20300899 | 0.83 | PDE2A (0.31) | HSD11B1 | |
| SCHEMBL20301399 | 0.80 | — | — | |
| SCHEMBL20301369 | 0.80 | PDE2A (0.32) | — | |
| SCHEMBL20301193 | 0.80 | NPC1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018116072-A1 | HETEROCYCLIC COMPOUNDS | PI INDUSTRIES LTD. (IN) | 2018-06-28 | — | — | WO | claimed |
| WO-2018116072-A1 | HETEROCYCLIC COMPOUNDS | PI INDUSTRIES LTD. (IN) | 2018-06-28 | — | — | WO | disclosed |