Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MBNL1 | Q9NR56 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20300767 | 0.89 | KDM4E (0.31) | MBNL1KDM4E | |
| SCHEMBL20301236 | 0.89 | MBNL1 (0.39) | MBNL1NPC1KDM4EPDE10ARPS6KA2 | |
| SCHEMBL20300844 | 0.88 | MBNL1 (0.35) | MBNL1NPC1KDM4EPDE10AADORA2A | |
| SCHEMBL20300689 | 0.88 | NPC1 (0.35) | MBNL1NPC1BACE1ALDH1A1MAPT | |
| SCHEMBL20301186 | 0.88 | KDM4E (0.36) | MBNL1KDM4E | |
| SCHEMBL20300735 | 0.86 | KDM4E (0.33) | KDM4E | |
| SCHEMBL20300743 | 0.86 | KDM4E (0.35) | KDM4EPDE10APDE2AALDH1A1 | |
| SCHEMBL20301949 | 0.85 | ACP1 (0.37) | KDM4EBACE1 | |
| SCHEMBL20301394 | 0.85 | KMT2A (0.35) | MBNL1KDM4E | |
| SCHEMBL20301474 | 0.82 | NPC1 (0.40) | MBNL1NPC1KDM4EPDE10AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018116072-A1 | HETEROCYCLIC COMPOUNDS | PI INDUSTRIES LTD. (IN) | 2018-06-28 | — | — | WO | claimed |
| WO-2018116072-A1 | HETEROCYCLIC COMPOUNDS | PI INDUSTRIES LTD. (IN) | 2018-06-28 | — | — | WO | disclosed |