SCHEMBL2030203

SCHEMBL2030203

CN[C@H](Cc1ccc(OCc2ccccc2)cc1)C(=O)O

nearest known ligand 0.67

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PPARG P37231 10/20 0.67
MME P08473 1/20 0.63
ACE P12821 1/20 0.63
CPA1 P15085 1/20 0.63
ACE2 Q9BYF1 1/20 0.63
GPR34 Q9UPC5 4/20 0.62
MMP9 P14780 1/20 0.62
MMP8 P22894 1/20 0.62
PPARA Q07869 3/20 0.60
LTA4H P09960 1/20 0.57
PPARD Q03181 1/20 0.57
GPR132 Q9UNW8 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8760872 1.00 PPARG (0.67) PPARGMMEACECPA1ACE2
SCHEMBL2035189 1.00 PPARG (0.67) PPARGMMEACECPA1ACE2
SCHEMBL684726 0.90 PPARG (0.62) PPARGMMEACECPA1ACE2
SCHEMBL13227760 0.90 PPARG (0.62) PPARGMMEACECPA1ACE2
SCHEMBL13013217 0.90 PPARG (0.62) PPARGMMEACECPA1ACE2
SCHEMBL23901567 0.89 LTA4H (0.61) PPARGMMEACECPA1ACE2
SCHEMBL3499760 0.89 LTA4H (0.65) PPARGMMEACECPA1ACE2
SCHEMBL3499757 0.89 LTA4H (0.65) PPARGMMEACECPA1ACE2
SCHEMBL681310 0.88 MMP9 (0.59) PPARGMMEACECPA1ACE2
SCHEMBL10272198 0.88 MMP9 (0.59) PPARGMMEACECPA1ACE2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10633630-B2 Acceleration of Mycobacterium growth ST GEORGE'S HOSPITAL MEDICAL SCHOOL (GB) 2020-04-28 US disclosed
EP-3158053-B1 ACCELERATION OF MYCOBACTERIUM GROWTH ST GEORGES HOSPITAL MEDICAL SCHOOL (GB) 2019-03-13 EP disclosed
US-9707282-B2 Small cationic antimicrobial peptides THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2017-07-18 US disclosed
US-20170121672-A1 ACCELERATION OF MYCOBACTERIUM GROWTH ST GEORGE'S HOSPITAL MEDICAL SCHOOL (GB) 2017-05-04 US disclosed
US-20150315240-A1 SMALL CATIONIC ANTIMICROBIAL PEPTIDES THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2015-11-05 US disclosed
US-9017656-B2 Small cationic antimicrobial peptides THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2015-04-28 US disclosed
EP-2061886-B1 Small cationic immunomodulatory peptides UNIV BRITISH COLUMBIA (CA) 2014-05-07 EP disclosed
US-20130266597-A1 Small Cationic Antimicrobial Peptides THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2013-10-10 US disclosed
US-8343475-B2 Small cationic antimicrobial peptides THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2013-01-01 US disclosed
US-20110236429-A1 Small Cationic Antimicrobial Peptides THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2011-09-29 US disclosed
US-20110150917-A1 Small Cationic Antimicrobial Peptides THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2011-06-23 US disclosed
EP-2061886-A1 SMALL CATIONIC ANTIMICROBIAL PEPTIDES The University of British Columbia (CA) 2009-05-27 EP disclosed
WO-2008022444-A1 SMALL CATIONIC ANTIMICROBIAL PEPTIDES THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2008-02-28 WO disclosed