Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.44 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | GMNN | O75496 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CETP | P11597 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | UBE2N | P61088 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18038633 | 0.91 | TRPV1 (0.48) | TRPV1TRPA1SPHK1LMNACYP2D6 | |
| SCHEMBL11508064 | 0.88 | TRPV1 (0.46) | TRPV1TRPA1SPHK1LMNACYP2D6 | |
| SCHEMBL11346601 | 0.88 | TRPV1 (0.42) | TRPV1TRPA1SPHK1LMNACYP2D6 | |
| 1,3-Butanediol SCHEMBL28244301 | 0.88 | TSHR (0.43) | TRPV1TRPA1LMNAALDH1A1HSD17B10 | |
| 1,6-Hexanediol SCHEMBL2190350 | 0.88 | TSHR (0.43) | TRPV1TRPA1LMNAALDH1A1HSD17B10 | |
| 1,5-Pentanediol SCHEMBL6423642 | 0.88 | TSHR (0.43) | TRPV1TRPA1LMNAALDH1A1HSD17B10 | |
| SCHEMBL4954833 | 0.86 | TRPV1 (0.42) | TRPV1TRPA1SPHK1LMNACYP2D6 | |
| 1,3-Butanediol SCHEMBL8093341 | 0.85 | TDP1 (0.44) | TRPV1TRPA1LMNAALDH1A1HSD17B10 | |
| SCHEMBL4425494 | 0.85 | THRB (0.38) | TRPV1TRPA1SPHK1LMNACYP2D6 | |
| 1,3-Butanediol SCHEMBL1415145 | 0.85 | TDP1 (0.44) | TRPV1TRPA1LMNAALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8481773-B2 | Volatile cyclic siloxanes | DOW CORNING CORPORATION (US) | 2013-07-09 | — | — | US | disclosed |
| US-20120276026-A1 | Volatile Cyclic Siloxanes | DOW SILICONES CORPORATION | 2012-11-01 | — | — | US | disclosed |
| EP-2504345-A1 | VOLATILE CYCLIC SILOXANES | Dow Corning Corporation (US) | 2012-10-03 | — | — | EP | disclosed |
| WO-2011071698-A1 | VOLATILE CYCLIC SILOXANES | DOW CORNING CORPORATION (US) | 2011-06-16 | — | — | WO | disclosed |
| WO-2011066359-A1 | PERSONAL CARE COMPOSITIONS CONTAINING CERTAIN CYCLIC SILOXANES | DOW CORNING CORPORATION (US) | 2011-06-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120276026-A1 | Volatile Cyclic Siloxanes | CCNB2, CCNA2, CCND2 | TRPV1 3381/4885TRPA1 966/4885SPHK1 1641/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.