Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | PLA2G4B | P0C869 | 5/20 | 0.47 |
| ▸ | ESR1 | P03372 | 2/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.46 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.46 |
| ▸ | RARB | P10826 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | NQO2 | P16083 | 1/20 | 0.45 |
| ▸ | PLA2G4A | P47712 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12585684 | 1.00 | TP53 (0.48) | TP53TSHRKDM4EALDH1A1HPGD | |
| SCHEMBL11660429 | 0.95 | TP53 (0.52) | TP53TSHRKDM4EALDH1A1HPGD | |
| SCHEMBL11659439 | 0.95 | TP53 (0.52) | TP53TSHRKDM4EALDH1A1HPGD | |
| SCHEMBL11656786 | 0.95 | TP53 (0.52) | TP53TSHRKDM4EALDH1A1HPGD | |
| SCHEMBL11332817 | 0.94 | ALDH1A1 (0.52) | TP53TSHRKDM4EALDH1A1HPGD | |
| SCHEMBL11332814 | 0.94 | ALDH1A1 (0.52) | TP53TSHRKDM4EALDH1A1HPGD | |
| SCHEMBL10635627 | 0.91 | TP53 (0.49) | TP53TSHRKDM4EALDH1A1HPGD | |
| SCHEMBL10635633 | 0.91 | TP53 (0.49) | TP53TSHRKDM4EALDH1A1HPGD | |
| SCHEMBL11656013 | 0.91 | TP53 (0.49) | TP53TSHRKDM4EALDH1A1HPGD | |
| SCHEMBL20156660 | 0.91 | ALDH1A1 (0.54) | TP53TSHRKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7959990-B2 | Adjustment of liquid crystals; oligomers, dendrimers, or polymer in solution is applied to support; crosslinking by radiation or polarized light | ROLIC AG (CH) | 2011-06-14 | — | — | US | disclosed |
| EP-1928979-B1 | FUNCTIONALIZED PHOTOREACTIVE COMPOUNDS | ROLIC AG (CH) | 2009-03-04 | — | — | EP | disclosed |
| US-20080274304-A1 | Functionalized Photoreactive Compounds | ROLIC AG (CH) | 2008-11-06 | — | — | US | disclosed |
| EP-1928979-A1 | FUNCTIONALIZED PHOTOREACTIVE COMPOUNDS | Rolic AG (CH) | 2008-06-11 | — | — | EP | disclosed |
| WO-2007033506-A1 | FUNCTIONALIZED PHOTOREACTIVE COMPOUNDS | ROLIC AG (CH) | 2007-03-29 | — | — | WO | disclosed |
| EP-1764405-A1 | Functionalized photoreactive compounds | Rolic AG (CH) | 2007-03-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080274304-A1 | Functionalized Photoreactive Compounds | PCNA, PIN1, MAP1LC3C | TP53 4824/4885TSHR 4847/4885KDM4E 2641/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.