Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP6 | P51161 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | PARP11 | Q9NR21 | 2/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | ALPL | P05186 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 6/20 | 0.34 |
| ▸ | JAK2 | O60674 | 5/20 | 0.34 |
| ▸ | JAK1 | P23458 | 2/20 | 0.34 |
| ▸ | JAK3 | P52333 | 2/20 | 0.34 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.34 |
| ▸ | ROS1 | P08922 | 1/20 | 0.34 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18594591 | 0.80 | ALDH1A1 (0.45) | FABP6GRM5ALDH1A1GAAMAPT | |
| SCHEMBL701202 | 0.78 | FABP6 (0.50) | FABP6GSK3BPARP11ALPLALDH1A1 | |
| SCHEMBL22210654 | 0.77 | ALDH1A1 (0.57) | FABP6GRM5ALDH1A1GAAMAPT | |
| SCHEMBL2061574 | 0.76 | FABP6 (0.54) | FABP6GSK3BPARP11ALDH1A1GAA | |
| SCHEMBL10274616 | 0.76 | ALDH1A1 (0.56) | FABP6GSK3BPARP11GRM5ALDH1A1 | |
| SCHEMBL15586859 | 0.76 | FABP6 (0.48) | FABP6GSK3BPARP11ALPLALDH1A1 | |
| SCHEMBL19386434 | 0.75 | PARP11 (0.61) | PARP11GRM5PARP10 | |
| SCHEMBL16014463 | 0.75 | FABP6 (0.47) | FABP6GSK3BPARP11ALPLALDH1A1 | |
| SCHEMBL29731708 | 0.75 | PRMT5 (0.49) | FABP6GSK3BALDH1A1GAA | |
| SCHEMBL2994247 | 0.73 | MAOA (0.58) | FABP6GSK3BALDH1A1MAPTMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10005774-B2 | Syk inhibitors | GILEAD SCIENCES, INC. (US) | 2018-06-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10005774-B2 | Syk inhibitors | SYK, BTK, LYN | FABP6 4824/4885GSK3B 209/4885PARP11 643/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.