Acrylic Acid

Acrylic Acid

SCHEMBL2030660

C=CC(=O)O.O=S(=O)(O)O.OCCO

nearest known ligand 0.56

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Known targets — ChEMBL curated mechanism

ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3CALCRLCHRM1CHRM2CHRM3F2RMAOAMAOBMAP2K1MAP2K2NTRK1NTRK2NTRK3OPRD1OPRK1OPRM1P2RY12PKLRSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASLC18A2SLC6A2SLC6A3TLR7TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8dacAdacBdacCfolAftsImrcAmrcBmrdApolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmB1rpmB2rpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmHrpmIrpmJrpmJ2rpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsR1rpsR2rpsSrpsTrpsUrpsZykgMykgO

The experimentally established mechanism targets of Acrylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.56
ALOX15 P16050 1/20 0.41
HSD17B10 Q99714 1/20 0.41
TSHR P16473 4/20 0.37
CA5A P35218 1/20 0.33
CA5B Q9Y2D0 1/20 0.33
ALDH1A1 P00352 4/20 0.32
FGFR4 P22455 1/20 0.32
MAPK1 P28482 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acrylic Acid SCHEMBL11406925 0.88 LMNA (0.71) LMNAALOX15HSD17B10TSHRALDH1A1
Acrylic Acid SCHEMBL1101285 0.88 LMNA (0.71) LMNAALOX15HSD17B10TSHRALDH1A1
Acrylic Acid SCHEMBL15955850 0.88 LMNA (0.71) LMNAALOX15HSD17B10TSHRALDH1A1
Acrylic Acid SCHEMBL25515 0.88 LMNA (0.71) LMNAALOX15HSD17B10TSHRALDH1A1
Acrylic Acid SCHEMBL29707305 0.88 LMNA (0.71) LMNAALOX15HSD17B10TSHRALDH1A1
Acrylic Acid SCHEMBL29457256 0.88 LMNA (0.71) LMNAALOX15HSD17B10TSHRALDH1A1
Acrylic Acid SCHEMBL36466 0.88
Acrylic Acid SCHEMBL2524668 0.88 LMNA (0.71) LMNAALOX15HSD17B10TSHRALDH1A1
Acrylic Acid SCHEMBL3399482 0.88 LMNA (0.71) LMNAALOX15HSD17B10TSHRCA5A
Acrylic Acid SCHEMBL562913 0.85 LMNA (0.67) LMNAALOX15HSD17B10TSHRCA5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2507326-B1 CRYSTALLINE COLLOIDAL ARRAY OF PARTICLES BEARING REACTIVE SURFACTANT PPG IND OHIO INC (US) 2020-07-29 EP claimed
EP-2507326-A1 CRYSTALLINE COLLOIDAL ARRAY OF PARTICLES BEARING REACTIVE SURFACTANT PPG Industries Ohio, Inc. (US) 2012-10-10 EP claimed
US-20110135888-A1 CRYSTALLINE COLLOIDAL ARRAY OF PARTICLES BEARING REACTIVE SURFACTANT PPG INDUSTRIES OHIO, INC. (US) 2011-06-09 US claimed
WO-2011068942-A1 CRYSTALLINE COLLOIDAL ARRAY OF PARTICLES BEARING REACTIVE SURFACTANT PPG INDUSTRIES OHIO, INC. (US) 2011-06-09 WO claimed
EP-2507326-B1 CRYSTALLINE COLLOIDAL ARRAY OF PARTICLES BEARING REACTIVE SURFACTANT PPG IND OHIO INC (US) 2020-07-29 EP disclosed
EP-2507326-A1 CRYSTALLINE COLLOIDAL ARRAY OF PARTICLES BEARING REACTIVE SURFACTANT PPG Industries Ohio, Inc. (US) 2012-10-10 EP disclosed
US-20110135888-A1 CRYSTALLINE COLLOIDAL ARRAY OF PARTICLES BEARING REACTIVE SURFACTANT PPG INDUSTRIES OHIO, INC. (US) 2011-06-09 US disclosed
WO-2011068942-A1 CRYSTALLINE COLLOIDAL ARRAY OF PARTICLES BEARING REACTIVE SURFACTANT PPG INDUSTRIES OHIO, INC. (US) 2011-06-09 WO disclosed