SCHEMBL2030735

SCHEMBL2030735

C=CC(=C)C.C=CC(C)CO

nearest known ligand 0.50

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.50
ALDH1A1 P00352 1/20 0.50
TP53 P04637 1/20 0.50
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL313933 0.87
SCHEMBL7883560 0.87
SCHEMBL7889185 0.87
Isobutanol SCHEMBL27930417 0.81 TSHR (0.59) TSHRALDH1A1TP53TDP1
SCHEMBL10862988 0.75 ALDH1A1 (0.67) TSHRALDH1A1TP53
Phosphoric Acid SCHEMBL21683370 0.75 LAP3 (0.32) TSHRTDP1
Nitrous Acid SCHEMBL7088089 0.75
Isobutane SCHEMBL8544268 0.74
Glycerin SCHEMBL6274859 0.74 ALDH1A1 (0.56) TSHRALDH1A1TP53TDP1
Alcohol SCHEMBL472182 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2756082-A1 MICROORGANISMS AND METHODS FOR PRODUCING ALKENES Genomatica, Inc. (US) 2014-07-23 EP disclosed
WO-2013040383-A1 MICROORGANISMS AND METHODS FOR PRODUCING ALKENES GENOMATICA, INC. (US) 2013-03-21 WO disclosed
WO-2011076691-A1 METHOD FOR PRODUCING AN ALKENE COMPRISING THE STEP OF CONVERTING AN ALCOHOL BY AN ENZYMATIC DEHYDRATION STEP MARLIERE PHILIPPE (FR) 2011-06-30 WO disclosed