Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPG | P10696 | 6/20 | 0.40 |
| ▸ | ALPL | P05186 | 5/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 3/20 | 0.35 |
| ▸ | CA2 | P00918 | 3/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA7 | P43166 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.35 |
| ▸ | XDH | P47989 | 1/20 | 0.35 |
| ▸ | PLAA | Q9Y263 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10040807 | 0.87 | ALPL (0.33) | ALPGALPLHPGDALDH1A1RAB9A | |
| Adrenalone SCHEMBL123124 | 0.81 | ALPG (0.55) | ALPGALPLHDAC6CA1CA2 | |
| Adrenalone SCHEMBL29550997 | 0.81 | ALPG (0.55) | ALPGALPLHDAC6CA1CA2 | |
| Adrenalone SCHEMBL6662605 | 0.80 | ALPG (0.54) | ALPGALPLHDAC6CA1CA2 | |
| Adrenalone SCHEMBL28668200 | 0.78 | ALPG (0.52) | ALPGALPLHDAC6CA1CA2 | |
| SCHEMBL15942999 | 0.75 | CA1 (0.53) | HDAC6CA1CA2CA12CA7 | |
| SCHEMBL3278783 | 0.73 | CA12 (0.59) | HDAC6CA1CA2CA12CA7 | |
| SCHEMBL13885946 | 0.73 | KDM4E (0.50) | HDAC6CA1CA2CA12CA7 | |
| SCHEMBL10390729 | 0.73 | POLB (0.49) | ALPGALPLHDAC6ALDH1A1RAB9A | |
| SCHEMBL29071120 | 0.71 | HSD17B3 (0.55) | ALPGCA1CA2CA12CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2951281-B1 | SYSTEM AND METHOD FOR MIMICKING HEART FUNCTION | UNIV CENTRAL FLORIDA RES FOUND INC (US) | 2018-06-27 | — | — | EP | disclosed |