Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPG | P10696 | 9/20 | 0.55 |
| ▸ | ALPL | P05186 | 8/20 | 0.55 |
| ▸ | CA12 | O43570 | 3/20 | 0.53 |
| ▸ | CA1 | P00915 | 3/20 | 0.53 |
| ▸ | CA2 | P00918 | 3/20 | 0.53 |
| ▸ | CA7 | P43166 | 3/20 | 0.53 |
| ▸ | CA9 | Q16790 | 3/20 | 0.53 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.53 |
| ▸ | XDH | P47989 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
| ▸ | CA6 | P23280 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | PLAA | Q9Y263 | 6/20 | 0.49 |
| ▸ | DBH | P09172 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adrenalone SCHEMBL123124 | 1.00 | ALPG (0.55) | ALPGALPLCA12CA1CA2 | |
| Adrenalone SCHEMBL6662605 | 0.98 | ALPG (0.54) | ALPGALPLCA12CA1CA2 | |
| Adrenalone SCHEMBL28668200 | 0.96 | ALPG (0.52) | ALPGALPLCA12CA1CA2 | |
| SCHEMBL6046293 | 0.81 | ALPG (0.52) | ALPGALPLCA12CA1CA2 | |
| SCHEMBL7441728 | 0.81 | ALPG (0.52) | ALPGALPLCA12CA1CA2 | |
| SCHEMBL20310071 | 0.81 | ALPG (0.40) | ALPGALPLCA12CA1CA2 | |
| SCHEMBL14646958 | 0.81 | ALPG (0.51) | ALPGALPLCA12CA1CA2 | |
| SCHEMBL31419971 | 0.80 | ALPG (0.51) | ALPGALPLCA12CA1CA2 | |
| SCHEMBL29391092 | 0.80 | KDM4E (0.53) | ALPGALPLCA12CA1CA2 | |
| SCHEMBL9768178 | 0.80 | KDM4E (0.53) | ALPGALPLCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4686757-A1 | INHIBITORS OF EXPRESSION AND/OR FUNCTION | e-therapeutics PLC (GB) | 2026-02-04 | — | — | EP | disclosed |
| EP-3607962-B1 | ANGIOTENSIN II ALONE OR IN COMBINATION FOR THE TREATMENT OF HYPOTENSION | THE GEORGE WASHINGTON UNIV A CONGRESSIONALLY CHARTERED NOT FOR PROFIT CORPORATION (US) | 2025-08-13 | — | — | EP | disclosed |
| CN-114206885-B | Pyrazolo [3,4-B ] pyrazines SHP2 phosphatase inhibitors | 大冢制药株式会社 | 2025-05-02 | — | — | CN | disclosed |
| CN-119700926-A | Angiotensin II alone or in combination for the treatment of hypotension | 乔治华盛顿大学国会特许非营利公司 | 2025-03-28 | — | — | CN | disclosed |
| CN-119403542-A | Injectable suspension | 伊勒卓菲公司 | 2025-02-07 | — | — | CN | disclosed |
| CN-118369091-A | Isolated trans isomer of 3- (2-bromo-3, 4-dihydroxy-phenyl) -N- (3, 4, 5-trihydroxy-benzyl) -thioacrylamide | 特尔诺沃有限公司 | 2024-07-19 | — | — | CN | disclosed |
| CN-116672456-A | Methods and compositions for TUSC2 immunotherapy | 得克萨斯州大学系统董事会 | 2023-09-01 | — | — | CN | disclosed |
| US-20230226141-A1 | ANGIOTENSIN II ALONE OR IN COMBINATION FOR THE TREATMENT OF HYPOTENSION | THE GEORGE WASHINGTON UNIV A CONGRESSIONALLY CHARTERED NOT FOR PROFIT CORPORATION (US) | 2023-07-20 | — | — | US | disclosed |
| EP-3558267-B1 | A MUCOADHESIVE OROMUCOSAL FORMULATION COMPRISING A NICOTINE COMPLEX | FERTIN PHARMA AS (DK) | 2023-04-26 | — | — | EP | disclosed |
| US-11559559-B2 | Angiotensin II alone or in combination for the treatment of hypotension | THE GEORGE WASHINGTON UNIVERSITY, A CONGRESSIONALLY CHARTERED NOT-FOR-PROFIT CORPORATION (US) | 2023-01-24 | — | — | US | disclosed |
| US-20220047669-A1 | ANGIOTENSIN II ALONE OR IN COMBINATION FOR THE TREATMENT OF HYPOTENSION | THE GEORGE WASHINGTON UNIVERSITY, A CONGRESSIONALLY CHARTERED NOT-FOR-PROFIT CORPORATION | 2022-02-17 | — | — | US | disclosed |