Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 10/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | DPP7 | Q9UHL4 | 6/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 5/20 | 0.41 |
| ▸ | DPP4 | P27487 | 5/20 | 0.41 |
| ▸ | DPP9 | Q86TI2 | 5/20 | 0.41 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.38 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25682244 | 0.81 | PSMB5 (0.49) | PSMB5CYP2C9DPP7DPP8DPP4 | |
| SCHEMBL25682249 | 0.79 | PSMB5 (0.47) | PSMB5CYP2C9DPP7DPP8DPP4 | |
| SCHEMBL15060447 | 0.74 | DPP4 (0.50) | PSMB5CYP2C9DPP7DPP8DPP4 | |
| SCHEMBL11892766 | 0.70 | LMNA (0.53) | CYP2C9 | |
| SCHEMBL9917049 | 0.69 | CYP2C9 (0.50) | PSMB5CYP2C9 | |
| SCHEMBL4863908 | 0.69 | — | — | |
| SCHEMBL7604693 | 0.69 | — | — | |
| SCHEMBL875553 | 0.69 | — | — | |
| SCHEMBL10053615 | 0.67 | DPP7 (0.43) | PSMB5DPP7DPP8DPP4DPP9 | |
| SCHEMBL155431 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180179232-A1 | BORONIC ACID DERIVATIVES | MERCK PATENT GMBH (DE) | 2018-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180179232-A1 | BORONIC ACID DERIVATIVES | BCL9, BCL9L, BCL6 | PSMB5 105/4885CYP2C9 4374/4885DPP7 187/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.