Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | FNTA | P49354 | 1/20 | 0.32 |
| ▸ | FNTB | P49356 | 1/20 | 0.32 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.32 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | CCR6 | P51684 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31501278 | 0.88 | CYP2C9 (0.45) | CYP2C9MEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL3027896 | 0.83 | CYP2C9 (0.41) | CYP2C9KMT2AALDH1A1POLBLMNA | |
| SCHEMBL11001077 | 0.80 | HDAC3 (0.48) | MEN1KMT2AFNTAFNTBPSMB5 | |
| SCHEMBL13402414 | 0.77 | CYP2C9 (0.48) | CYP2C9MEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL10001823 | 0.77 | CYP2C9 (0.48) | CYP2C9MEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL18164083 | 0.77 | CYP2C9 (0.48) | CYP2C9MEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL16644753 | 0.75 | CYP2C9 (0.46) | CYP2C9MEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL8247706 | 0.75 | CYP2C9 (0.46) | CYP2C9MEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL16628179 | 0.75 | CYP2C9 (0.46) | CYP2C9MEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL18483161 | 0.75 | CYP2C9 (0.46) | CYP2C9MEN1KMT2AALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120149710-A1 | SORTASE A INHIBITORS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2012-06-14 | — | — | US | disclosed |
| US-7511063-B2 | High affinity quinoline-based kinase ligands | SCHERING CORPORATION (US) | 2009-03-31 | — | — | US | disclosed |
| US-20080045568-A1 | Novel high affinity quinoline-based kinase ligands | SCHERING CORPORATION | 2008-02-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149710-A1 | SORTASE A INHIBITORS | STS, ENGASE, SPR | CYP2C9 1965/4885MEN1 3994/4885KMT2A 3208/4885 |
| US-20080045568-A1 | Novel high affinity quinoline-based kinase ligands | CDKL2, CDK2, CDKL1 | CYP2C9 4575/4885MEN1 2423/4885KMT2A 418/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.