Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 7/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | AHR | P35869 | 1/20 | 0.35 |
| ▸ | TTR | P02766 | 2/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20317290 | 0.86 | MAOA (0.42) | MAOAALDH1A1KDM4ENPC1LMNA | |
| SCHEMBL20317286 | 0.86 | MAOA (0.42) | MAOAALDH1A1KDM4ENPC1LMNA | |
| SCHEMBL20317226 | 0.86 | MAOA (0.44) | MAOAALDH1A1KDM4ENPC1LMNA | |
| SCHEMBL19662669 | 0.85 | MAOA (0.49) | MAOAALDH1A1KDM4ENPC1LMNA | |
| SCHEMBL20329914 | 0.85 | MAOA (0.56) | MAOAALDH1A1MAOBKDM4ENPC1 | |
| SCHEMBL20317308 | 0.84 | AR (0.39) | MAOAALDH1A1MAOBDYRK1AKDM4E | |
| SCHEMBL20317313 | 0.84 | AR (0.39) | MAOAALDH1A1MAOBDYRK1AKDM4E | |
| SCHEMBL20317326 | 0.83 | ALDH1A1 (0.39) | MAOAALDH1A1MAOBDYRK1ANPC1 | |
| SCHEMBL20317295 | 0.82 | MAOA (0.63) | MAOAALDH1A1MAOBKDM4ENPC1 | |
| SCHEMBL20317281 | 0.82 | MAOA (0.63) | MAOAALDH1A1MAOBKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180179174-A1 | 12H-BENZO[b]XANTHEN-12-ONES, COMPOSITIONS CONTAINING, AND USES OF, SAME | THESAN PHARMACEUTICALS, INC. (US) | 2018-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180179174-A1 | 12H-BENZO[b]XANTHEN-12-ONES, COMPOSITIONS CONTAINING, AND USES OF, SAME | AHR, NR1H2, NR1H3 | MAOA 408/4885ALDH1A1 1200/4885MAOB 220/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.