Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.35 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21840205 | 1.00 | ALDH1A1 (0.39) | ALDH1A1KMT2AMEN1GAALPAR1 | |
| SCHEMBL21938657 | 1.00 | ALDH1A1 (0.39) | ALDH1A1KMT2AMEN1GAALPAR1 | |
| SCHEMBL21840247 | 0.82 | ALDH1A1 (0.38) | ALDH1A1KMT2AMEN1LPAR1 | |
| SCHEMBL20320099 | 0.82 | ALDH1A1 (0.38) | ALDH1A1KMT2AMEN1LPAR1 | |
| SCHEMBL20320133 | 0.82 | ALDH1A1 (0.38) | ALDH1A1KMT2AMEN1LPAR1 | |
| SCHEMBL21938529 | 0.81 | TLR9 (0.35) | KMT2AMEN1GAAPPP1CACA2 | |
| SCHEMBL20320246 | 0.81 | TLR9 (0.35) | KMT2AMEN1GAAPPP1CACA2 | |
| SCHEMBL21840254 | 0.81 | TLR9 (0.35) | KMT2AMEN1GAAPPP1CACA2 | |
| SCHEMBL20320268 | 0.81 | TLR9 (0.35) | KMT2AMEN1GAAPPP1CACA2 | |
| SCHEMBL22906305 | 0.80 | ALDH1A1 (0.33) | ALDH1A1KMT2AMEN1LPAR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3555102-B1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2021-01-20 | — | — | EP | disclosed |
| WO-2018114584-A1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2018-06-28 | — | — | WO | disclosed |