Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20320099 | 1.00 | ALDH1A1 (0.38) | ALDH1A1CYP3A4POLBPKMKMT2A | |
| SCHEMBL21840247 | 1.00 | ALDH1A1 (0.38) | ALDH1A1CYP3A4POLBPKMKMT2A | |
| SCHEMBL21840205 | 0.82 | ALDH1A1 (0.39) | ALDH1A1KMT2ALPAR1MEN1 | |
| SCHEMBL21938657 | 0.82 | ALDH1A1 (0.39) | ALDH1A1KMT2ALPAR1MEN1 | |
| SCHEMBL20320102 | 0.82 | ALDH1A1 (0.39) | ALDH1A1KMT2ALPAR1MEN1 | |
| SCHEMBL20320130 | 0.79 | ALDH1A1 (0.36) | ALDH1A1CYP3A4POLBPKMKMT2A | |
| SCHEMBL21840238 | 0.79 | KMT2A (0.32) | ALDH1A1CYP3A4POLBKMT2ALPAR1 | |
| SCHEMBL20320143 | 0.79 | KMT2A (0.32) | ALDH1A1CYP3A4POLBKMT2ALPAR1 | |
| SCHEMBL22906306 | 0.79 | KMT2A (0.32) | ALDH1A1CYP3A4POLBKMT2ALPAR1 | |
| SCHEMBL20320105 | 0.79 | KMT2A (0.32) | ALDH1A1CYP3A4POLBKMT2ALPAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3555102-B1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2021-01-20 | — | — | EP | disclosed |
| WO-2018114584-A1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2018-06-28 | — | — | WO | disclosed |