Di(Hydroxyethyl)Ether

Di(Hydroxyethyl)Ether

SCHEMBL20320673

C=C.O=C(O)c1cccc(C(=O)O)c1S(=O)(=O)O.OCCCCO.OCCO.OCCOCCO

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 2/20 0.39
ALDH1A1 P00352 3/20 0.38
KMT2A Q03164 1/20 0.38
PTK2B Q14289 1/20 0.38
HTT P42858 1/20 0.34
CYP2D6 P10635 1/20 0.34
CNR2 P34972 3/20 0.33
CNR1 P21554 2/20 0.33
S1PR3 Q99500 1/20 0.33
CA12 O43570 2/20 0.32
CA9 Q16790 2/20 0.32
KDM4E B2RXH2 2/20 0.32
CA2 P00918 2/20 0.32
MAPT P10636 1/20 0.32
TSHR P16473 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
HNF4A P41235 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Di(Hydroxyethyl)Ether SCHEMBL4324073 0.91 ALOX15 (0.45) ALOX15ALDH1A1KMT2APTK2BCYP2D6
Di(Hydroxyethyl)Ether SCHEMBL6363998 0.91 ALOX15 (0.45) ALOX15ALDH1A1KMT2APTK2BCYP2D6
Ethylene Glycol SCHEMBL8066613 0.87 ALOX15 (0.49) ALOX15ALDH1A1CYP2D6CA12CA9
Ethylene Glycol SCHEMBL5604837 0.83 ALOX15 (0.52) ALOX15ALDH1A1KMT2ACYP2D6CA12
Ethylene Glycol SCHEMBL2116930 0.83 ALOX15 (0.52) ALOX15ALDH1A1KMT2ACYP2D6CA12
Isophthalic Acid SCHEMBL8371405 0.83 CYP2C19 (0.42) ALOX15ALDH1A1KMT2APTK2BCYP2D6
SCHEMBL27318264 0.81 TSHR (0.44) ALOX15ALDH1A1KMT2ACNR2CNR1
Ethylene SCHEMBL3394557 0.80 ALOX15 (0.55) ALOX15ALDH1A1CYP2D6CA12CA9
SCHEMBL2116927 0.78 ALOX15 (0.41) ALOX15ALDH1A1KMT2ACYP2D6KDM4E
Ethylene SCHEMBL4534557 0.78 ALOX15 (0.53) ALOX15ALDH1A1CYP2D6CA12CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10011734-B2 Coated film MITSUBISHI CHEMICAL CORPORATION (JP) 2018-07-03 US disclosed