Ethylene Glycol

Ethylene Glycol

SCHEMBL5604837

O=C(O)c1cccc(C(=O)O)c1S(=O)(=O)O.OCCO.OCCO

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 2/20 0.52
ALDH1A1 P00352 6/20 0.44
CYP2D6 P10635 1/20 0.44
KDM4E B2RXH2 3/20 0.41
TSHR P16473 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
HNF4A P41235 1/20 0.40
NR4A1 P22736 1/20 0.39
NR4A2 P43354 1/20 0.39
NR4A3 Q92570 1/20 0.39
CA1 P00915 2/20 0.39
CA2 P00918 2/20 0.39
MMP2 P08253 2/20 0.39
MMP1 P03956 1/20 0.39
MMP9 P14780 1/20 0.39
MMP8 P22894 1/20 0.39
MMP13 P45452 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
LMNA P02545 1/20 0.39
MAPT P10636 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene Glycol SCHEMBL2116930 1.00 ALOX15 (0.52) ALOX15ALDH1A1CYP2D6KDM4ETSHR
Ethylene Glycol SCHEMBL8066613 0.96 ALOX15 (0.49) ALOX15ALDH1A1CYP2D6KDM4ETSHR
Terephthalic Acid SCHEMBL8092861 0.93 ALOX15 (0.46) ALOX15ALDH1A1CYP2D6KDM4ETSHR
Benzene SCHEMBL10638262 0.92 ALOX15 (0.59) ALOX15ALDH1A1CYP2D6KDM4ETSHR
SCHEMBL65889 0.92 ALOX15 (0.59) ALOX15ALDH1A1CYP2D6KDM4ETSHR
SCHEMBL3781304 0.90 ALOX15 (0.57) ALOX15ALDH1A1CYP2D6KDM4ETSHR
SCHEMBL20471934 0.90 ALOX15 (0.57) ALOX15ALDH1A1CYP2D6KDM4ETSHR
SCHEMBL812165 0.90 ALOX15 (0.57) ALOX15ALDH1A1CYP2D6KDM4ETSHR
Phosphine SCHEMBL3820807 0.90 ALOX15 (0.57) ALOX15ALDH1A1CYP2D6KDM4ETSHR
Ammonia Solution, Strong SCHEMBL3299235 0.90 ALOX15 (0.57) ALOX15ALDH1A1CYP2D6KDM4ETSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230103602-A1 AQUEOUS COATING COMPOSITION AND MULTILAYERED COATING FILM FORMATION METHOD NIPPON PAINT AUTOMOTIVE COATINGS CO., LTD. (JP) 2023-04-06 US disclosed
EP-4112190-A1 AQUEOUS COATING COMPOSITION AND MULTILAYERED COATING FILM FORMATION METHOD Nippon Paint Automotive Coatings Co., Ltd. (JP) 2023-01-04 EP disclosed
US-7271216-B2 Polyurethane resin aqueous dispersion and sheet material obtained from the same SANYO CHEMICAL INDUSTRIES, LTD. (JP) 2007-09-18 US disclosed
US-20060111510-A1 Polyurethane resin aqueous despersion and sheet material obtained from the same SANYO CHEMICAL INDUSTRIES, LTD. (JP) 2006-05-25 US disclosed
EP-1600464-A1 AQUEOUS POLYURETHANE RESIN DISPERSION AND SHEET MATERIAL OBTAINED FROM THE SAME Sanyo Chemical Industries, Ltd. (JP) 2005-11-30 EP disclosed