SCHEMBL203213

SCHEMBL203213

CCCC(N)CCOc1cccc(C(N)=O)c1

nearest known ligand 0.54

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.54
PARP1 P09874 1/20 0.51
SMPD1 P17405 3/20 0.47
PRSS1 P07477 7/20 0.46
TNKS O95271 1/20 0.46
PARP15 Q460N3 1/20 0.46
PARP14 Q460N5 1/20 0.46
PARP10 Q53GL7 1/20 0.46
TNKS2 Q9H2K2 1/20 0.46
PARP2 Q9UGN5 1/20 0.46
PLA2G4B P0C869 1/20 0.44
TAS1R3 Q7RTX0 1/20 0.44
TAS1R1 Q7RTX1 1/20 0.44
NR1H4 Q96RI1 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL201441 0.85 KMT2A (0.52) KMT2APARP1SMPD1PRSS1TNKS
SCHEMBL201524 0.84 KMT2A (0.73) KMT2APARP1SMPD1PRSS1TNKS
SCHEMBL201949 0.83 NR1H4 (0.60) KMT2APARP1PRSS1TNKSPARP15
SCHEMBL201450 0.83 KMT2A (0.62) KMT2APARP1SMPD1PRSS1TNKS
SCHEMBL201933 0.82 PARP1 (0.53) KMT2APARP1SMPD1PRSS1TNKS
SCHEMBL203104 0.81 SMPD1 (0.68) KMT2APARP1SMPD1PRSS1PLA2G4B
SCHEMBL201242 0.80 SMPD1 (0.70) KMT2APARP1SMPD1PRSS1PLA2G4B
SCHEMBL202777 0.80 SMPD1 (0.70) KMT2APARP1SMPD1PRSS1PLA2G4B
SCHEMBL12951117 0.80 SMPD1 (0.70) KMT2APARP1SMPD1PRSS1PLA2G4B
SCHEMBL202638 0.80 SMPD1 (0.70) KMT2APARP1SMPD1PRSS1PLA2G4B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250179008-A1 ANTIBACTERIAL AGENTS TAXIS PHARMACEUTICALS, INC. (US) 2025-06-05 US disclosed
US-20150191420-A1 ANTIBACTERIAL AGENTS TAXIS PHARMACEUTICALS, INC. 2015-07-09 US disclosed
US-8865736-B2 Antibacterial agents Biota Scientific Pty Ltd (AU) 2014-10-21 US disclosed
US-20130072520-A2 ANTIBACTERIAL AGENTS BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) 2013-03-21 US disclosed
US-20120122918-A1 ANTIBACTERIAL AGENTS BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) 2012-05-17 US disclosed
US-8088791-B2 Antibacterial agents Biots Scientific Management Pty Ltd (AU) 2012-01-03 US disclosed
EP-1996180-B1 BENZAMIDE AND PYRIDYLAMIDE DERIVATIVES AS ANTIBACTERIAL AGENTS BIOTA EUROPE LTD (GB) 2011-08-03 EP disclosed
US-20100173933-A1 ANTIBACTERIAL AGENTS PROLYSIS LTD (GB) 2010-07-08 US disclosed
EP-1996180-A1 ANTIBACTERIAL AGENTS Prolysis Limited (GB) 2008-12-03 EP disclosed
WO-2007107758-A1 ANTIBACTERIAL AGENTS PROLYSIS LTD (GB) 2007-09-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120122918-A1 ANTIBACTERIAL AGENTS ALK, ROS1, ARG1 KMT2A 380/4885PARP1 1024/4885SMPD1 1528/4885
US-20130072520-A2 ANTIBACTERIAL AGENTS ALK, ROS1, NOX1 KMT2A 1011/4885PARP1 1034/4885SMPD1 1055/4885
US-20150191420-A1 ANTIBACTERIAL AGENTS ALK, ARG1, ROS1 KMT2A 415/4885PARP1 1040/4885SMPD1 1525/4885
US-20250179008-A1 ANTIBACTERIAL AGENTS ALK, ROS1, NOX1 KMT2A 1011/4885PARP1 1034/4885SMPD1 1055/4885
US-20100173933-A1 ANTIBACTERIAL AGENTS ALK, ROS1, NOX1 KMT2A 1011/4885PARP1 1034/4885SMPD1 1055/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.