SCHEMBL20323328

SCHEMBL20323328

COc1cc(C)ccc1OCOc1ccc(C)cc1OC

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.71
L3MBTL1 Q9Y468 12/20 0.62
MAPT P10636 10/20 0.62
HPGD P15428 5/20 0.62
ALDH1A1 P00352 4/20 0.62
CYP2C9 P11712 3/20 0.62
CYP2C19 P33261 3/20 0.62
POLB P06746 3/20 0.62
MAPK1 P28482 2/20 0.62
MEN1 O00255 1/20 0.62
USP2 O75604 1/20 0.62
ALOX12 P18054 1/20 0.62
KMT2A Q03164 1/20 0.62
NPSR1 Q6W5P4 1/20 0.62
L3MBTL4 Q8NA19 1/20 0.59
L3MBTL3 Q96JM7 1/20 0.59
RAB9A P51151 4/20 0.57
NPC1 O15118 3/20 0.57
SMN1; SMN2 Q16637 4/20 0.56
KDM4E B2RXH2 3/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12375199 0.92 ACHE (0.65) ACHEL3MBTL1MAPTHPGDALDH1A1
SCHEMBL7634998 0.85 ACHE (0.68) ACHEL3MBTL1MAPTHPGDALDH1A1
SCHEMBL29403877 0.84 ACHE (1.00) ACHEL3MBTL1MAPTHPGDALDH1A1
SCHEMBL12518 0.84 ACHE (1.00) ACHEL3MBTL1MAPTHPGDALDH1A1
SCHEMBL12408754 0.83 ACHE (0.65) ACHEL3MBTL1MAPTHPGDALDH1A1
SCHEMBL20615140 0.83 ACHE (0.65) ACHEL3MBTL1MAPTHPGDALDH1A1
SCHEMBL30802160 0.83 ACHE (0.52) ACHEL3MBTL1MAPTHPGDALDH1A1
SCHEMBL11890520 0.83 ACHE (0.52) ACHEL3MBTL1MAPTHPGDALDH1A1
SCHEMBL10196613 0.82 L3MBTL1 (0.67) ACHEL3MBTL1MAPTHPGDALDH1A1
SCHEMBL8256686 0.82 L3MBTL1 (0.72) ACHEL3MBTL1MAPTHPGDALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018115113-A1 PROCESS FOR TREATING KERATIN FIBRES WITH A PHOTOCROSSLINKABLE POLYVINYL ALCOHOL L'OREAL (FR) 2018-06-28 WO disclosed